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非洲动脉瘤性蛛网膜下腔出血诊断工具获取与血管内治疗的大陆性调查。

Continental Survey of Access to Diagnostic Tools and Endovascular Management of Aneurysmal Subarachnoid Hemorrhage in Africa.

作者信息

Dokponou Yao Christian Hugues, Kotecha Jay, Bandyopadhyay Soham, Erhabor Joshua, Ooi Setthasorn Zhi Yang, Egiz Abdullah, Boutarbouch Mahjouba, Dalle David Ulrich, Higginbotham George, Thioub Mbaye, Sichimba Dawin, Bankole Nourou Dine Adeniran, Kanmounye Ulrick Sidney

机构信息

Research Department, Association of Future African Neurosurgeons, Yaounde, Cameroon.

Department of Neurosurgery, Mohammed V University, Rabat, Morocco.

出版信息

Front Surg. 2021 Jul 20;8:690714. doi: 10.3389/fsurg.2021.690714. eCollection 2021.

Abstract

Interventional neurovascular procedures are effective in lowering the burden of mortality and complications resulting from aneurysmal subarachnoid hemorrhage (aSAH). Despite the wide uptake of interventional neurovascular procedures in high-income countries, access to care in low- and middle-income countries remains limited, and little is known about accessibility in Africa. In this survey, we decided to assess access to diagnostic tools and treatment of aSAH in Africa. A Google form e-survey was distributed to African neurosurgery centers accepting responses from January 4th to March 21st 2021. Data on accessibility to diagnostic tools, treatment methodologies, and interventional neuroradiology personnel in African centers were collected. Ninety five percent confidence intervals were computed for each variable. Data was received from 36 neurosurgical centers in 16 African countries (16/54, 30%). Most centers were public institutions. Ninety four percent of the centers had the necessary resources for a lumbar puncture (LP) and a laboratory for the diagnosis of aSAH. Most centers had at least one computed tomography (CT) scanner, 81% of the centers had access to CT angiography and some had access to conventional angiography. Forty seven percent of the centers could obtain a head CT within 2 h of presentation in an emergency. Sixty one percent of centers provided clipping of intracranial aneurysms whilst only 22% of centers could perform the endovascular treatment. Sixty four percent of centers did not have an endovascular specialist. This survey highlights health inequity in access to endovascular treatment for aSAH. Lack of diagnostic tools to identify an aneurysm and a shortfall of qualified endovascular specialists are prime reasons for this. Our findings can inform health system strengthening policies including the acquisition of equipment and capacity building in Africa.

摘要

介入神经血管手术在降低动脉瘤性蛛网膜下腔出血(aSAH)导致的死亡率和并发症负担方面是有效的。尽管高收入国家广泛采用介入神经血管手术,但低收入和中等收入国家获得治疗的机会仍然有限,而关于非洲的可及性情况知之甚少。在这项调查中,我们决定评估非洲对aSAH的诊断工具和治疗的可及性。通过谷歌表单进行了一项电子调查,向非洲神经外科中心发放,接受2021年1月4日至3月21日的回复。收集了非洲各中心在诊断工具可及性、治疗方法和介入神经放射学人员方面的数据。为每个变量计算了95%置信区间。收到了来自16个非洲国家36个神经外科中心的数据(16/54,30%)。大多数中心是公共机构。94%的中心具备进行腰椎穿刺(LP)和诊断aSAH的实验室所需资源。大多数中心至少有一台计算机断层扫描(CT)扫描仪,81%的中心可以进行CT血管造影,一些中心可以进行传统血管造影。47%的中心在紧急情况下能够在就诊后2小时内获得头部CT。61%的中心提供颅内动脉瘤夹闭术,而只有22%的中心能够进行血管内治疗。64%的中心没有血管内治疗专家。这项调查突出了在aSAH血管内治疗可及性方面的健康不平等。缺乏识别动脉瘤的诊断工具和合格血管内治疗专家的短缺是主要原因。我们的研究结果可为加强卫生系统政策提供参考,包括在非洲购置设备和进行能力建设。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/020a/8329527/643c91d24f3a/fsurg-08-690714-g0001.jpg

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