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Deprescribing in palliative care.舒缓治疗中的减药。
Clin Med (Lond). 2019 Jul;19(4):311-314. doi: 10.7861/clinmedicine.19-4-311.
2
Deprescribing at the end of life in older patients.老年患者临终时的减药处理
JAAPA. 2019 Jul;32(7):20-24. doi: 10.1097/01.JAA.0000558316.40245.ca.
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Overview of results from the Vitamin D Assessment (ViDA) study.维生素 D 评估(ViDA)研究结果概述。
J Endocrinol Invest. 2019 Dec;42(12):1391-1399. doi: 10.1007/s40618-019-01056-z. Epub 2019 May 23.
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Nurses' Perspectives on Family Caregiver Medication Management Support and Deprescribing.护士对家庭照顾者药物管理支持及减药的看法。
J Hosp Palliat Nurs. 2019 Aug;21(4):312-318. doi: 10.1097/NJH.0000000000000574.
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2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.2019美国心脏病学会/美国心脏协会心血管疾病一级预防指南:美国心脏病学会/美国心脏协会临床实践指南工作组报告
J Am Coll Cardiol. 2019 Sep 10;74(10):e177-e232. doi: 10.1016/j.jacc.2019.03.010. Epub 2019 Mar 17.
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Communication Techniques for Deprescribing Conversations #369.减药谈话的沟通技巧 #369
J Palliat Med. 2019 Mar;22(3):335-336. doi: 10.1089/jpm.2018.0669.
7
Associations Between Polypharmacy, Symptom Burden, and Quality of Life in Patients with Advanced, Life-Limiting Illness.在患有晚期、生命有限疾病的患者中,药物滥用、症状负担和生活质量之间的关联。
J Gen Intern Med. 2019 Apr;34(4):559-566. doi: 10.1007/s11606-019-04837-7. Epub 2019 Feb 4.
8
Tools for Deprescribing in Frail Older Persons and Those with Limited Life Expectancy: A Systematic Review.衰弱老年人和预期寿命有限人群的减药工具:系统评价。
J Am Geriatr Soc. 2019 Jan;67(1):172-180. doi: 10.1111/jgs.15616. Epub 2018 Oct 13.
9
Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly.阿司匹林对健康老年人心血管事件和出血的影响。
N Engl J Med. 2018 Oct 18;379(16):1509-1518. doi: 10.1056/NEJMoa1805819. Epub 2018 Sep 16.
10
Deprescribing: A simple method for reducing polypharmacy.减药:一种减少多重用药的简单方法。
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临终关怀患者的撤药:停用阿司匹林、多种维生素和他汀类药物。

Deprescribing in Hospice Patients: Discontinuing Aspirin, Multivitamins, and Statins.

作者信息

Low Cari E, Sanchez Pellecer Daniel E, Santivasi Wil L, Thompson Virginia H, Elwood Theresa, Davidson Ashly J, Tlusty Julie A, Feely Molly A, Ingram Cory

机构信息

Mayo Clinic School of Graduate Medical Education, Mayo Clinic College of Medicine and Science, Rochester, MN.

Mayo Clinic Hospice, Mayo Clinic, Rochester, MN.

出版信息

Mayo Clin Proc Innov Qual Outcomes. 2021 Jul 24;5(4):721-726. doi: 10.1016/j.mayocpiqo.2021.06.010. eCollection 2021 Aug.

DOI:10.1016/j.mayocpiqo.2021.06.010
PMID:34355129
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8325098/
Abstract

OBJECTIVE

To facilitate deprescribing of aspirin, multivitamins, and statins in hospice patients enrolled in Mayo Clinic Hospice, Rochester, Minnesota.

PATIENTS AND METHODS

During the fall of 2019, we conducted a quality improvement project to improve care of Mayo Clinic Hospice patients by decreasing the percentage of patients taking aspirin, multivitamins, or statins. Project interventions included the addition of a palliative medicine fellow to the hospice interdisciplinary team, nurse education, and implementation of an evidence-based deprescribing resource tool. The resource tool included a communication framework to guide deprescribing conversations and a literature summary supporting deprescribing. The project team recorded the number of patients taking 1 of these medications by intermittently surveying the hospice census. Process and counterbalance measures were tracked with online surveys of hospice nursing staff.

RESULTS

At the start of the project, 22 of 69 patients (32%) were taking aspirin, a multivitamin, or a statin. After introduction of the deprescribing resource tool and the addition of a palliative medicine fellow to the interdisciplinary team, this was reduced to 20 of 83 patients (24%), a 24% decrease. Results appeared to be driven primarily by a reduction in multivitamin use (33% decrease). Self-reported comfort and knowledge about deprescribing improved among the hospice nursing staff, as did satisfaction in their workflow from 5.4 to 6.0 (maximum, 7).

CONCLUSION

The addition of a dedicated team member to address medication issues and provision of an evidence-based deprescribing resource tool appear to reduce the use of unnecessary and potentially harmful medications in ambulatory hospice patients.

摘要

目的

在明尼苏达州罗切斯特市梅奥诊所临终关怀项目登记的临终关怀患者中,促进停用阿司匹林、多种维生素和他汀类药物。

患者与方法

2019年秋季,我们开展了一项质量改进项目,通过降低服用阿司匹林、多种维生素或他汀类药物的患者比例,改善梅奥诊所临终关怀患者的护理。项目干预措施包括在临终关怀跨学科团队中增加一名姑息医学研究员、护士教育以及实施基于证据的减药资源工具。该资源工具包括一个指导减药谈话的沟通框架和一份支持减药的文献综述。项目团队通过间歇性调查临终关怀患者普查记录服用这些药物之一的患者数量。通过对临终关怀护理人员的在线调查跟踪过程和平衡措施。

结果

项目开始时,69名患者中有22名(32%)服用阿司匹林、多种维生素或他汀类药物。在引入减药资源工具并在跨学科团队中增加一名姑息医学研究员后,这一比例降至83名患者中的20名(24%),下降了24%。结果似乎主要是由于多种维生素使用的减少(下降了33%)。临终关怀护理人员自我报告的对减药的舒适度和知识有所提高,他们对工作流程的满意度也从5.4提高到了6.0(满分7分)。

结论

增加一名专门的团队成员来处理用药问题以及提供基于证据的减药资源工具,似乎可以减少门诊临终关怀患者中不必要和潜在有害药物的使用。