Grasso Rosario Francesco, Andresciani Flavio, Altomare Carlo, Pacella Giuseppina, Castiello Gennaro, Carassiti Massimiliano, Quattrocchi Carlo Cosimo, Faiella Eliodoro, Beomonte Zobel Bruno
Department of Diagnostic and Interventional Radiology, University Hospital Campus Bio-Medico of Rome, Via Alvaro del Portillo, 200, 00128 Rome, Italy.
Unit of Anesthesia, Intensive Care and Pain Management, University Hospital Campus Bio-Medico of Rome, Via Alvaro del Portillo, 200, 00128 Rome, Italy.
Biology (Basel). 2021 Jul 11;10(7):646. doi: 10.3390/biology10070646.
(1) Background: The aim of this retrospective study is to assess safety and efficacy of lung radiofrequency (RFA) and microwave ablation (MWA) using an augmented reality computed tomography (CT) navigation system (SIRIO) and to compare it with the standard CT-guided technique. (2) Methods: Lung RFA and MWA were performed with an augmented reality CT 3D navigation system (SIRIO) in 52 patients. A comparison was then performed with a group of 49 patients undergoing the standard CT-guided technique. All the procedures were divided into four groups based on the lesion diameter (>2 cm or ≤2 cm), and procedural time, the number of CT scans, radiation dose administered, and complications rate were evaluated. Technical success was defined as the presence of a "ground glass" area completely covering the target lesion at the immediate post-procedural CT. (3) Results: Full technical success was achieved in all treated malignant lesions for all the considered groups. SIRIO-guided lung thermo-ablations (LTA) displayed a significant decrease in the number of CT scans, procedure time, and patients' radiation exposure ( < 0.001). This also resulted in a dosage reduction in hypnotics and opioids administrated for sedation during LTA. No significant differences were observed between the SIRIO and non-SIRIO group in terms of complications incidence. (4) Conclusions: SIRIO is an efficient tool to perform CT-guided LTA, displaying a significant reduction ( < 0.001) in the number of required CT scans, procedure time, and patients' radiation exposure.
(1) 背景：本回顾性研究旨在评估使用增强现实计算机断层扫描（CT）导航系统（SIRIO）进行肺射频消融（RFA）和微波消融（MWA）的安全性和有效性，并将其与标准CT引导技术进行比较。(2) 方法：对52例患者使用增强现实CT三维导航系统（SIRIO）进行肺RFA和MWA。然后与一组49例接受标准CT引导技术的患者进行比较。所有手术根据病变直径（>2 cm或≤2 cm）分为四组，并评估手术时间、CT扫描次数、辐射剂量和并发症发生率。技术成功定义为术后即刻CT显示“磨玻璃”区域完全覆盖目标病变。(3) 结果：所有考虑的组中，所有治疗的恶性病变均取得了完全的技术成功。SIRIO引导的肺热消融（LTA）在CT扫描次数、手术时间和患者辐射暴露方面均显著减少（<0.001）。这也导致LTA期间用于镇静的催眠药和阿片类药物剂量减少。SIRIO组和非SIRIO组在并发症发生率方面未观察到显著差异。(4) 结论：SIRIO是进行CT引导LTA的有效工具，在所需CT扫描次数、手术时间和患者辐射暴露方面显著减少（<0.001）。
