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经导管主动脉瓣植入术的进展:重点更新。

Advancements in Transcatheter Aortic Valve Implantation: A Focused Update.

机构信息

Structural Interventional Cardiology, Department of Clinical and Experimental Medicine, Clinica Medica, Room 124, Careggi University Hospital, Largo Brambilla 3, 50139 Florence, Italy.

出版信息

Medicina (Kaunas). 2021 Jul 14;57(7):711. doi: 10.3390/medicina57070711.

Abstract

Transcatheter aortic valve implantation (TAVI) has become the leading technique for aortic valve replacement in symptomatic patients with severe aortic stenosis with conventional surgical aortic valve replacement (SAVR) now limited to patients younger than 65-75 years due to a combination of unsuitable anatomies (calcified raphae in bicuspid valves, coexistent aneurysm of the ascending aorta) and concerns on the absence of long-term data on TAVI durability. This incredible rise is linked to technological evolutions combined with increased operator experience, which led to procedural refinements and, accordingly, to better outcomes. The article describes the main and newest technical improvements, allowing an extension of the indications (valve-in-valve procedures, intravascular lithotripsy for severely calcified iliac vessels), and a reduction of complications (stroke, pacemaker implantation, aortic regurgitation).

摘要

经导管主动脉瓣植入术(TAVI)已成为严重主动脉瓣狭窄症状患者主动脉瓣置换的主要技术,而传统的外科主动脉瓣置换术(SAVR)由于解剖结构不合适(二叶式主动脉瓣的钙化嵴,升主动脉并存的动脉瘤)以及对 TAVI 耐久性缺乏长期数据的担忧,现在仅限于 65-75 岁以下的患者。这种惊人的增长与技术进步相结合,再加上手术医生经验的增加,导致了手术方法的改进,进而带来了更好的结果。本文描述了主要的和最新的技术改进,这些改进使得适应证得到扩展(瓣中瓣手术、严重钙化的髂血管的腔内碎石术),并减少了并发症(中风、起搏器植入、主动脉瓣反流)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a4f/8306774/1e4cb6301d79/medicina-57-00711-g001.jpg

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