Meeroff J C, de Larrechea I, Meeroff M
Am J Gastroenterol. 1977 Nov;68(5):441-51.
Little doubt exists concerning the limited usefulness of gastric analysis as a screening test in unselected populations. Reliable tests, such as those for glycemia, are also of limited value when performed blindly on the general population. When, however, gastric analysis is performed on an adequate preselected population, it has a valuable role in the diagnosis and management of several gastroduodenal diseases. Highly satisfactory results can be obtained when the proper population is selected because errors are minimized due to an increased prevalence of diseases. We have verified the reliability of two types of gastric analyses: the conventional method of gastric analysis based on measurement of acid output alone (CGA) and the so-called gastroionogram (GIG), in 100 consecutive gastric analyses using the method proposed by Kronborg. Gastroionogram increases specificity (even at the risk of decreasing sensitivity) and provides an excellent predictive value of the test. With the same conditions CGA is less useful because of the overlapping among normal and diseased groups. It is useful, however, for separating patients into three groups of normal secretors, hyposecretors and hypersecretors.
对于胃分析作为一种在未经过挑选的人群中进行筛查的检测方法，其作用有限这一点几乎没有疑问。可靠的检测方法，如血糖检测，在对普通人群盲目进行检测时，价值也有限。然而，当对经过充分预先挑选的人群进行胃分析时，它在几种胃十二指肠疾病的诊断和管理中具有重要作用。当选择了合适的人群时，可以获得非常令人满意的结果，因为由于疾病患病率的增加，误差被最小化。我们使用克朗伯格提出的方法，对连续100例胃分析病例，验证了两种胃分析方法的可靠性：仅基于胃酸分泌量测量的传统胃分析方法（CGA）和所谓的胃离子图（GIG）。胃离子图提高了特异性（即使有降低敏感性的风险），并提供了出色的检测预测价值。在相同条件下，由于正常组和患病组之间存在重叠，CGA的作用较小。然而，它对于将患者分为正常分泌者、低分泌者和高分泌者三组是有用的。
