Monteiro Diana Paula Pandochi Fernandes, Correa Marcos, Neto Thomaz Talarico, Martinelli Carlos Eduardo, Filho Hugo Tourinho
School of Physical Education and Sport of Ribeirao Preto, University of São Paulo, Ribeirao Preto, Brazil.
School of Physical Education and Sport of Ribeirao Preto, University of São Paulo, Ribeirao Preto, Brazil.
Growth Horm IGF Res. 2021 Oct-Dec;60-61:101420. doi: 10.1016/j.ghir.2021.101420. Epub 2021 Jul 30.
Bodybuilding involves athletes performing a series of poses/postures on the stage so that they can be classified according to their best esthetic and physical appearance during the competition. In the weeks prior to the target competition, the athletes subject themselves to restrictive diets and different physical training methods, as well as using dietary supplementation and, in some cases, anabolic steroids, to reduce body fat to low levels and maintain or increase muscle mass. On the other hand, it is known that physical training is a potent stimulator for releasing the components of the GH/IGF-I axis that are directly linked to the anabolic process. Based on these assumptions, this study aimed to verify the kinetics of IGF-I and of its binding protein IGFBP-3 in female bodybuilders. Serum IGF-I and IGFBP-3 concentrations were recorded before and after standardized training sessions at two different times: in the initial phase (phase 1) and in the final phase of the pre-contest (phase 2) of a 12-week training season. It was possible to conclude that there was a significant reduction in serum IGF-I values at the end of the pre-contest phase that preceded the athletes' participation in a competition. With relation to the serum IGF-I and IGFBP-3 values measured before and after the standardized training session, it was only possible to verify significant changes in the IGF-I values in the initial phase of the pre-contest. It seems reasonable to suggest that the caloric restriction used by bodybuilders may be related to the decrease in IGF-I values verified at the end of the pre-contest phase.
健美运动要求运动员在舞台上展示一系列姿势，以便根据他们在比赛中最佳的美学和身体外观进行分类。在目标比赛前的几周里，运动员会进行严格的饮食控制和采用不同的体能训练方法，还会使用膳食补充剂，在某些情况下甚至使用合成代谢类固醇，以将体脂降至低水平并维持或增加肌肉量。另一方面，众所周知，体育锻炼是释放生长激素/胰岛素样生长因子-I轴中与合成代谢过程直接相关成分的有力刺激因素。基于这些假设，本研究旨在验证女性健美运动员体内胰岛素样生长因子-I及其结合蛋白胰岛素样生长因子结合蛋白-3的动力学变化。在为期12周的训练赛季的两个不同时间点，即初始阶段（第1阶段）和赛前最后阶段（第2阶段），在标准化训练课程前后记录血清胰岛素样生长因子-I和胰岛素样生长因子结合蛋白-3的浓度。可以得出结论，在运动员参加比赛前的赛前阶段结束时，血清胰岛素样生长因子-I值显著降低。关于标准化训练课程前后测量的血清胰岛素样生长因子-I和胰岛素样生长因子结合蛋白-3值，仅在赛前初始阶段的胰岛素样生长因子-I值中发现了显著变化。似乎有理由认为，健美运动员所采用的热量限制可能与赛前阶段结束时胰岛素样生长因子-I值的降低有关。
