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火鸡的免疫活性细胞:T和B淋巴细胞的年龄及器官分布模式

Immunocompetent cells of the turkey: age and organ distribution patterns of T and B lymphoid cells.

作者信息

Sivanandan V, Maheswaran S K

出版信息

Am J Vet Res. 1978 Feb;39(2):351-3.

PMID:343669
Abstract

The percentage of lymphoid cells from the bursa of Fabricius, thymus, spleen, peripheral blood, and cecal tonsils reactin with chicken antisera to turkey bursa and thymus were evaluated, using 1-day-old to 5-week-old turkeys. For this, rabbit anti-chicken globulin fluorescein isothiocyanate conjugate was used. The percentage of lymphoid cells showing immunoglobulin surface determinants from these organs also was examined, using a direct immunofluorescence test with a rabbit anti-turkey globulin fluorescein isothiocyanate conjugate. This study suggests that the bursa-specific antigen and immunoglobulin surface determinants could be used as markers for bursa-derived cells in the turkey. It also was found that thymus-specific antigen could be used as a marker for thymus-derived cells.

摘要

利用1日龄至5周龄的火鸡,评估了来自法氏囊、胸腺、脾脏、外周血和盲肠扁桃体的淋巴细胞与鸡抗火鸡法氏囊和胸腺抗血清发生反应的百分比。为此,使用了兔抗鸡球蛋白异硫氰酸荧光素缀合物。还使用兔抗火鸡球蛋白异硫氰酸荧光素缀合物进行直接免疫荧光试验,检测了这些器官中显示免疫球蛋白表面决定簇的淋巴细胞百分比。本研究表明,法氏囊特异性抗原和免疫球蛋白表面决定簇可作为火鸡中法氏囊来源细胞的标志物。还发现胸腺特异性抗原可作为胸腺来源细胞的标志物。

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