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种植体植入同期行牙槽嵴劈开术时使用自体骨和生物活性玻璃治疗水平骨缺损:一项随机临床试验

Autogenous Bone and Bioactive Glass around Implants Placed Simultaneously with Ridge Splitting for the Treatment of Horizontal Bony Defects: A Randomised Clinical Trial.

作者信息

Elamrousy Walid, Osama Mohamed, Issa Dalia Rasheed

机构信息

Periodontology Department, Faculty of Dentistry, Kafrelsheikh University, Kafr El-Sheikh 21614, Egypt.

Clinical Implantology Department, Faculty of Dentistry, Alexandria University, Alexandria 17862, Egypt.

出版信息

Int J Dent. 2021 Jul 28;2021:2457328. doi: 10.1155/2021/2457328. eCollection 2021.

DOI:10.1155/2021/2457328
PMID:34367287
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8337152/
Abstract

OBJECTIVE

To compare using autogenous bone with or without bioactive glass in ridge splitting of horizontal bone defects combined with simultaneous implant placement.

MATERIALS AND METHODS

In control group, bone expansion was performed and autogenous bone was used to augment the intercortical bone defect. In study group, autogenous bone was mixed with bioactive glass (1 : 1 in volume). In both groups, the implants were inserted simultaneously with ridge splitting. Six months following implant insertion, bone width and height were evaluated. Statistical analysis utilizing paired Student's -test was used for comparing results within the same group, whereas independent samples -test was used for intergroup variables comparison.

RESULTS

The mean bone width and labial and mesiodistal crestal bone height values were increased significantly in both groups from baseline to 6 months postoperatively. Comparing the two groups showed nonstatistical significant difference regarding the labial crestal bone loss, while the ridge width gain values were significantly higher in the study group than in the control group. The mesiodistal bone loss was significantly higher in control group than in study group.

CONCLUSION

Autogenous bone was mixed with bioactive glass (1 : 1 in volume) to fill intercortical defect created after ridge splitting to decrease peri-implant bone resorption associated with autogenous bone alone. This trial is registered with clinical trial registration: NCT04814160.

摘要

目的

比较在水平骨缺损嵴劈开同期种植时使用自体骨与使用自体骨联合生物活性玻璃的效果。

材料与方法

对照组进行骨扩张,使用自体骨增加皮质间骨缺损。研究组将自体骨与生物活性玻璃按体积比1∶1混合。两组均在嵴劈开的同时植入种植体。种植体植入6个月后,评估骨宽度和高度。采用配对t检验进行统计分析,以比较同一组内的结果,而采用独立样本t检验进行组间变量比较。

结果

两组从基线到术后6个月,平均骨宽度、唇侧和近远中牙槽嵴顶骨高度值均显著增加。两组唇侧牙槽嵴骨吸收无统计学显著差异,而研究组的嵴宽度增加值显著高于对照组。对照组的近远中骨吸收显著高于研究组。

结论

将自体骨与生物活性玻璃按体积比1∶1混合,填充嵴劈开后形成的皮质间缺损,以减少单纯自体骨相关的种植体周围骨吸收。本试验已在临床试验注册中心注册:NCT04814160。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/a9d869733af0/IJD2021-2457328.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/b5bd8712271f/IJD2021-2457328.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/9991f289c1c4/IJD2021-2457328.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/f07f4bcb6458/IJD2021-2457328.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/d82bcbdfa445/IJD2021-2457328.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/581f57e6ada6/IJD2021-2457328.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/a9d869733af0/IJD2021-2457328.006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/b5bd8712271f/IJD2021-2457328.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/9991f289c1c4/IJD2021-2457328.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/f07f4bcb6458/IJD2021-2457328.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/d82bcbdfa445/IJD2021-2457328.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/581f57e6ada6/IJD2021-2457328.005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8d2/8337152/a9d869733af0/IJD2021-2457328.006.jpg

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