ElAmrousy Walid, Issa Dalia Rasheed
Department of Oral Medicine and Periodontology, Faculty of Oral and Dental Medicine, Kafrelsheikh University, Kafr El-sheikh, Egypt.
Int J Dent. 2022 Feb 22;2022:4951455. doi: 10.1155/2022/4951455. eCollection 2022.
Autogenous tooth bone graft (ATBG) was suggested as a source for bone grafting materials, especially as they have similar chemical composition to bone. This study goal was to assess the clinical and radiographic consequences of ATBG with or without L-PRF on bone deposition around immediate implants placed in periodontally hopeless sites.
26 patients, with periodontally diseased teeth, underwent random assignment to receive the surgical protocol either with L-PRF over ATBG around immediately inserted implants (test group) or without it (control group). Clinical examination was observed. Radiographically, bone changes horizontally and vertically to determine marginal bone loss (MBL) and mesiodistal bone changes were made at the base line and 6 and 9 months after implant insertion. Statistical analysis utilizing paired Student's -test was used for comparing results within the same group, whereas an independent-sample -test was used for intergroup variable comparison.
All implants met the criteria of success without any complications at the follow-up period. Nonsignificant differences were detected between horizontal bone alterations in both groups at 6 and 9 months ( > .001). The test group showed statistically significant lower MBL than the control group ( < .001). The mesiodistal bone gain in the test group was significantly higher than that of the control group at the 6-month period ( < .001). The mesiodistal bone loss in the control group was significantly higher than that of the test group at the 9-month period ( < .001).
The ATBG- L-PRF combination therapy enhances new bone formation and appeared to be a favorable procedure with immediate implant placement, particularly in severe periodontitis cases.
自体牙骨移植（ATBG）被认为是骨移植材料的一个来源，特别是因为它们的化学成分与骨相似。本研究的目的是评估在牙周无望部位即刻种植体周围使用或不使用富含白细胞的纤维蛋白（L-PRF）的自体牙骨移植对骨沉积的临床和影像学影响。
26例患有牙周病的患者被随机分配接受手术方案，即在即刻植入的种植体周围的自体牙骨移植上使用L-PRF（试验组）或不使用（对照组）。进行临床检查。在影像学上，在基线以及种植体植入后6个月和9个月时，测量水平和垂直方向的骨变化，以确定边缘骨丢失（MBL）和近远中骨变化。使用配对t检验进行统计分析以比较同一组内的结果，而使用独立样本t检验进行组间变量比较。
在随访期间，所有种植体均符合成功标准，无任何并发症。两组在6个月和9个月时水平骨改变之间未检测到显著差异（P>.001）。试验组的MBL在统计学上显著低于对照组（P<.001）。试验组在6个月时近远中骨增量显著高于对照组（P<.001）。对照组在9个月时近远中骨丢失显著高于试验组（P<.001）。
自体牙骨移植-L-PRF联合治疗可促进新骨形成，似乎是一种有利于即刻种植的方法，特别是在重度牙周炎病例中。
