Ciochon Urszula Maria, Sehested Per Cai, Skejø Hanne Pernille Bro, Miehe Jacob, Nørgaard Ina, Shekhrajka Nitesh
Department of Diagnostic Radiology, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark.
Department of Neurology, Aleris Hamlet Hospital, Aarhus, Denmark.
Radiol Case Rep. 2021 Jul 22;16(9):2768-2773. doi: 10.1016/j.radcr.2021.06.080. eCollection 2021 Sep.
Brain herniation into arachnoid granulation (BHAG) is a quite recently described controversial entity in terms of both etiology and clinical significance. It comprises a herniation of brain tissue into a presumed preexisting arachnoid granulation in dural venous sinuses, calvarium, meningeal or diploic veins. Most often described as an incidental finding in patients examined for unrelated pathologies, some BHAGs can possibly be related to headache, epilepsy or conditions with increased intracranial pressure such as idiopathic intracranial hypertension (IIH) or pseudotumor cerebri (PTC). The number of reported cases is low and there are only three more recently published observational studies on this subject with results lacking statistical significance due to relatively few BHAGs analyzed. Therefore, BHAGs still need an increased focus from both the radiologists and clinicians and more published studies and cases are necessary to help in understanding their factual meaning, clinical and treatment implications. In this article we describe three new cases of BHAGs to the literature, with patients presenting with different symptoms.
脑疝入蛛网膜颗粒（BHAG）是一种最近才被描述的，在病因和临床意义方面都存在争议的实体。它包括脑组织疝入硬脑膜静脉窦、颅骨、脑膜或板障静脉中一个假定预先存在的蛛网膜颗粒。BHAG最常被描述为在因无关病理情况接受检查的患者中偶然发现的情况，一些BHAG可能与头痛、癫痫或颅内压升高的病症有关，如特发性颅内高压（IIH）或假性脑瘤（PTC）。报告的病例数量较少，关于这个主题最近仅发表了三项观察性研究，由于分析的BHAG相对较少，结果缺乏统计学意义。因此，BHAG仍然需要放射科医生和临床医生更多的关注，需要更多已发表的研究和病例来帮助理解它们的实际意义、临床和治疗意义。在本文中，我们向文献中描述了三例新的BHAG病例，患者表现出不同的症状。
