Orgonikova Ivona, Mari Lorenzo, Giannasi Chiara, Batlle Martí Pumarola I, Behr Sebastien, Brocal Josep
Wear Referrals Veterinary Hospital, Bradbury, Stockton-on-Tees, UK.
Department of Animal Medicine and Surgery, Murine and Comparative Laboratory Unit, Autonomous University of Barcelona, Bellaterra (Cerdanyola del Vallès), Barcelona, Spain.
JFMS Open Rep. 2021 Jul 21;7(2):20551169211025449. doi: 10.1177/20551169211025449. eCollection 2021 Jul-Dec.
In this report we describe the occurrence of intracranial meningioma in two adult cats from the same litter. The location of the meningioma varied: one tumour was at the level of the brainstem, and the other was affecting the temporal and piriform lobes. The cat with the brainstem meningioma was treated with radiotherapy and the littermate had a rostrotentorial craniectomy for tumour removal. Both cats had a histopathological diagnosis of grade I meningioma of a predominantly fibrous subtype.
Cases of familial meningioma in cats have not previously been described in the veterinary literature. However, familial meningioma is well described in humans and it is possible that cases are underestimated in animals. We discuss the possible genetic background and other causes, as well as challenges we may face in veterinary medicine in identifying these associations.
在本报告中，我们描述了同窝出生的两只成年猫颅内脑膜瘤的发生情况。脑膜瘤的位置各不相同：一个肿瘤位于脑干水平，另一个影响颞叶和梨状叶。患有脑干脑膜瘤的猫接受了放射治疗，而同窝的另一只猫接受了颅前幕开颅手术以切除肿瘤。两只猫的组织病理学诊断均为主要为纤维亚型的I级脑膜瘤。
猫的家族性脑膜瘤病例此前在兽医文献中尚未有描述。然而，家族性脑膜瘤在人类中已有详细记载，动物病例可能被低估。我们讨论了可能的遗传背景和其他原因，以及在兽医学中识别这些关联时可能面临的挑战。
