University of Miami School of Medicine, Miami, FL, USA.
Top Antivir Med. 2021 Jun-Jul;29(3):355-360.
The Conference on Retroviruses and Opportunistic Infections (CROI) serves as one of the most highly visible platforms upon which researchers gather to share the most recent findings on HIV/AIDS and, recently, on SARS-CoV-2 research. Research presentations on the novel coronavirus SARS-CoV-2 have become an increasing fixture at the conference since it was first covered at last year's conference. Although CROI 2021 was virtual, the organizers coordinated a seamless platform for presentations and poster sessions that effectively engaged the audience. CROI 2021 had a strong showing in terms of basic science presentations on HIV-1 and on SARS-CoV-2. Highlights included new insights into some of the more elusive steps in the viral replication cycle as well as new findings on immune escape strategies employed by SARS-CoV-2. The new investigator workshop has become a valuable resource that can be used by early stage and established investigators alike to receive state-of-the-art updates on research areas that might be outside their immediate areas of research. The new investigator workshop featured engaging presentations on novel aspects of HIV-1 and SARS-CoV-2 replication, impact of host immunity on HIV-1 and SARS-CoV-2, and approaches to assessing viral reservoir dynamics and strategies for viral reservoir elimination.
逆转录病毒和机会性感染会议（CROI）是研究人员聚集在一起分享 HIV/AIDS 最新发现的最具知名度的平台之一，最近也包括 SARS-CoV-2 研究。自去年会议首次报道以来，关于新型冠状病毒 SARS-CoV-2 的研究报告在会议上的出现频率越来越高。尽管 CROI 2021 是虚拟会议，但组织者协调了一个无缝的演示和海报会议平台，有效地吸引了观众。CROI 2021 在 HIV-1 和 SARS-CoV-2 的基础科学报告方面表现出色。亮点包括对病毒复制周期中一些更难以捉摸的步骤的新见解，以及对 SARS-CoV-2 采用的免疫逃逸策略的新发现。新研究员研讨会已成为一种有价值的资源，可供早期和已建立的研究员使用，以接收可能不在其直接研究领域的研究领域的最新研究进展。新研究员研讨会的报告内容引人入胜，涵盖了 HIV-1 和 SARS-CoV-2 复制的新方面、宿主免疫对 HIV-1 和 SARS-CoV-2 的影响，以及评估病毒库动力学的方法和消除病毒库的策略。
