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2020 年 3 月至 5 月期间,瑞典斯德哥尔摩发生了一起 COVID-19 疫情,在疫情爆发期间出现了严重的症状,但在疫情爆发前后的死亡率较低。

Severe features during outbreak but low mortality observed immediately before and after a March-May 2020 COVID-19 outbreak in Stockholm, Sweden.

机构信息

Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden.

Division of Pathology, Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden; Department of Pathology and Cytology, Karolinska University Laboratory, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Int J Infect Dis. 2021 Sep;110:433-435. doi: 10.1016/j.ijid.2021.08.005. Epub 2021 Aug 8.

Abstract

OBJECTIVES

The aim of this study was to estimate how well the excess mortality reflected the burden of coronavirus disease 2019 (COVID-19)-related deaths during the March-May 2020 COVID-19 outbreak in Stockholm, Sweden, and whether the excess mortality during the outbreak might have resulted in a compensatory reduced mortality after the outbreak.

METHODS

Using previous 10-year or 5-year average mortality rates as a baseline, the excess mortality estimates before, during, and after the COVID-19 outbreak in March-May 2020 in Stockholm were compared.

RESULTS

Weekly death estimates revealed that the immediate pre-outbreak and post-outbreak all-cause mortality did not exceed to excess mortality regardless of whether previous 10-year or 5-year average mortality was used. Forty-three days after the start of the outbreak, 74.4% of the total excess mortality was reportedly explained by known COVID-19-related deaths, and the present study reports an update, showing that 15 weeks after the start of the outbreak, the reported COVID-19-related deaths explained >99% of the total excess mortality.

CONCLUSIONS

An exceptional outbreak feature of rapid excess mortality was observed. However, no excess but similarly low mortality was observed immediately prior to the outbreak and post-outbreak, thus emphasizing the severity of the first wave of the COVID-19 outbreak in Stockholm.

摘要

目的

本研究旨在评估 2020 年 3 月至 5 月瑞典斯德哥尔摩 COVID-19 爆发期间,超额死亡率反映 2019 年冠状病毒病(COVID-19)相关死亡负担的程度,以及 COVID-19 爆发期间的超额死亡率是否可能导致爆发后死亡人数减少。

方法

使用前 10 年或 5 年的平均死亡率作为基线,比较 2020 年 3 月至 5 月 COVID-19 爆发前、期间和之后斯德哥尔摩的超额死亡率估计。

结果

每周的死亡估计表明,无论使用前 10 年还是 5 年的平均死亡率,爆发前和爆发后的全因死亡率均未超过超额死亡率。在疫情爆发 43 天后,据报道,已知与 COVID-19 相关的死亡已解释了总超额死亡的 74.4%,本研究报告了一个更新结果,表明在疫情爆发 15 周后,报告的 COVID-19 相关死亡解释了总超额死亡的>99%。

结论

观察到异常爆发的快速超额死亡率特征。然而,在爆发前和爆发后,并没有出现超额死亡率,而是同样低的死亡率,因此强调了斯德哥尔摩 COVID-19 爆发第一波的严重性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f18c/8349439/b5d76aa7efb7/gr1_lrg.jpg

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