Drug Research Program, University of Helsinki, Viikinkaari 5E, Helsinki 00790, Finland.
Individualized Drug Therapy Research Program, University of Helsinki, Haartmaninkatu 8, Helsinki 00290, Finland.
Sci Signal. 2021 Aug 10;14(695):eabj5058. doi: 10.1126/scisignal.abj5058.
In this issue of , Kataru did two simple but powerful tweaks to the typical studies that aim to advance our understanding of proangiogenic interventions. They shifted the focus from the outside of the endothelial cell to the inside, and they chose not to deliver an angiogenic signal, but instead to release the brakes from an already existing signal.
在本期 中,Kataru 对旨在增进我们对促血管生成干预理解的典型研究进行了两项简单而有力的调整。他们将焦点从内皮细胞的外部转移到内部,并且他们选择不传递血管生成信号,而是释放已经存在的信号的制动器。