Furkalo N K, Lutaĭ M I, Simorot V N, Zaĭtseva V I
Kardiologiia. 1987 Nov;27(11):68-72.
The efficacy of nitrosorbide, corinfar and obsidan in preventing myocardial ischemia, induced by exercise or intravenous dipyridamole, was evaluated in 20 coronary patients. Nitrosorbide was found to be the most effective, and obsidan, the least effective, drug in preventing the steal syndrome. It is suggested that the efficiency of anti-anginal drugs is based on their effect on coronary flow control as well as hemodynamic determinants of myocardial oxygen requirements. The dipyridamole test can be used for the assessment of the effects of antianginal agents.
在20例冠心病患者中评估了硝异山梨酯、心脉舒通和奥昔丹在预防运动或静脉注射双嘧达莫诱发的心肌缺血方面的疗效。发现硝异山梨酯是预防窃血综合征最有效的药物，而奥昔丹是最无效的药物。提示抗心绞痛药物的疗效基于它们对冠状动脉血流控制以及心肌需氧量的血流动力学决定因素的作用。双嘧达莫试验可用于评估抗心绞痛药物的效果。
