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儿童急性骨关节炎感染常常是被忽视的多学科急症:除了技术技能之外。

Acute osteoarticular infections in children are frequently forgotten multidiscipline emergencies: beyond the technical skills.

作者信息

El-Sobky Tamer, Mahmoud Shady

机构信息

Division of Paediatric Orthopaedics, Department of Orthopaedic Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

出版信息

EFORT Open Rev. 2021 Jul 8;6(7):584-592. doi: 10.1302/2058-5241.6.200155. eCollection 2021 Jul.

Abstract

Acute osteoarticular infections (AOI) should be treated as top emergencies. The first few days following the inception of infection are ultra-critical to long-term prognosis.A comprehensive road map for management of childhood AOI is still lacking despite recent advances in microbiology and imaging (magnetic resonance imaging). The many faces of childhood AOI warrant a multidiscipline approach to management.Laboratory and imaging findings of are still debatable and should not overshadow or delay a management plan based on the experienced physician's clinical judgment.Ample evidence-based practice supports the use of a few days of intravenous antibiotic administration followed by oral therapy until correlative clinical and basic laboratory (acute phase reactants) results improve.The growing body of evidence on 'high-risk' children/neonates of AOI warrants continual clinical extra-vigilance in identifying these patient subsets.Open drainage and debridement remain the mainstay of treatment of septic hips, whereas for other joints the use of alternative surgical techniques should be individualized or on case-by-case basis.Because the consequences of misdiagnosis of AOI are usually grave and permanent, proactive treatment/overtreatment is justified in the event of unconfirmed but suspicious diagnosis. Cite this article: 2021;6:584-592. DOI: 10.1302/2058-5241.6.200155.

摘要

急性骨关节炎感染(AOI)应作为最紧急的情况进行治疗。感染开始后的最初几天对长期预后至关重要。尽管微生物学和影像学(磁共振成像)最近取得了进展,但仍缺乏针对儿童AOI管理的全面路线图。儿童AOI的多种表现形式需要多学科的管理方法。实验室和影像学检查结果仍存在争议,不应掩盖或延误基于经验丰富的医生临床判断的管理计划。大量循证实践支持在相关临床和基础实验室(急性期反应物)结果改善之前,先进行几天的静脉抗生素给药,然后改为口服治疗。关于AOI“高危”儿童/新生儿的证据越来越多,这就需要在识别这些患者亚组时持续保持临床格外警惕。开放引流和清创仍然是化脓性髋关节治疗的主要方法,而对于其他关节,替代手术技术的使用应个体化或根据具体情况而定。由于AOI误诊的后果通常严重且不可逆转,在诊断未得到证实但有怀疑的情况下,积极治疗/过度治疗是合理的。引用本文:2021;6:584 - 592。DOI:10.1302/2058 - 5241.6.200155

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f20e/8335954/0b5d4a231a6b/eor-6-584-g001.jpg

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