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一名接受术前放化疗后行局部切除的直肠癌患者的晚期复发:病例报告

Late Recurrence in a Rectal Cancer Patient Who Underwent Preoperative Chemoradiotherapy Followed by Local Excision: A Case Report.

作者信息

Han Jin Soo, Lim Seok-Byung, Park Jin-Hong, Hong Yong Sang

机构信息

Division of Colon and Rectal Surgery, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

Department of Radiation Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Ann Coloproctol. 2021 Jul;37(Suppl 1):S24-S27. doi: 10.3393/ac.2020.00073.0010. Epub 2021 Jul 27.

Abstract

Some patients who have undergone preoperative chemoradiotherapy (CRT) following surgery have been diagnosed with late recurrence more than 5 years after treatment, raising questions about the possible benefit extending surveillance beyond the recommended 5 years. In 2011, a 71-year-old male patient was diagnosed with T3N+ low-lying rectal cancer located 3 cm from the anal verge before undergoing long-course preoperative CRT. After CRT, the patient was reexamined and diagnosed with ycT1-2N0 lesion, so local excision (LE) was performed. The patient underwent intensive surveillance for up to 5 years, and no evidence of recurrence was found. At 74 months after surgery, the patient was hospitalized for a hematochezia, and local recurrence at the excision site and peritoneal seeding nodules were identified. Considering the late recurrence in this patient, it might be necessary to long-term follow-up beyond 5 years in patients with preoperative CRT followed by LE.

摘要

一些在手术后接受术前放化疗(CRT)的患者在治疗5年多后被诊断为晚期复发,这引发了关于将监测时间延长至推荐的5年以上是否可能有益的疑问。2011年,一名71岁男性患者在接受长疗程术前CRT前被诊断为距肛缘3 cm的T3N+低位直肠癌。CRT后,对患者进行复查并诊断为ycT1-2N0病变,因此进行了局部切除(LE)。该患者接受了长达5年的强化监测,未发现复发迹象。术后74个月,患者因便血住院,发现切除部位局部复发及腹膜种植结节。考虑到该患者的晚期复发情况,对于术前接受CRT并随后进行LE的患者,可能有必要进行5年以上的长期随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f21/8359695/2061ad35665f/ac-2020-00073-0010f1.jpg

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