Lenka Abhishek, Jankovic Joseph
Department of Neurology, Medstar Georgetown University Hospital, Washington, DC, United States.
Parkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, United States.
Front Neurol. 2021 Jul 26;12:684835. doi: 10.3389/fneur.2021.684835. eCollection 2021.
Tremor is the most commonly encountered movement disorder in clinical practice. A wide range of pathologies may manifest with tremor either as a presenting or predominant symptom. Considering the marked etiological and phenomenological heterogeneity, it would be desirable to develop a classification of tremors that reflects their underlying pathophysiology. The tremor task force of the International Parkinson Disease and Movement Disorders Society has worked toward this goal and proposed a new classification system. This system has remained a prime topic of scientific communications on tremor in recent times. The new classification is based on two axes: 1. based on the clinical features, history, and tremor characteristics and 2. based on the etiology of tremor. In this article, we discuss the key aspects of the new classification, review various tremor syndromes, highlight some of the controversies in the field of tremor, and share the potential future perspectives.
震颤是临床实践中最常见的运动障碍。多种病理情况可能表现为震颤,无论是作为首发症状还是主要症状。考虑到病因和现象学上的显著异质性,开发一种反映其潜在病理生理学的震颤分类方法是很有必要的。国际帕金森病和运动障碍协会的震颤特别工作组已朝着这一目标努力,并提出了一种新的分类系统。近年来,该系统一直是震颤科学交流的主要话题。新分类基于两个轴:1. 基于临床特征、病史和震颤特点;2. 基于震颤的病因。在本文中,我们讨论新分类的关键方面,回顾各种震颤综合征,突出震颤领域的一些争议,并分享潜在的未来展望。