Elble Rodger J
Department of Neurology, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
Curr Opin Neurol. 2016 Aug;29(4):507-12. doi: 10.1097/WCO.0000000000000347.
Essential tremor has not been defined or used consistently in clinical diagnosis and research. Other monosymptomatic disorders are often referred to as essential tremor variants.
There is now solid evidence that essential tremor, however defined, is a syndrome with multiple causes.
A new tremor classification scheme is being developed by the International Parkinson and Movement Disorder Society Task Force on Tremor. In this scheme, tremor in the absence of other neurological signs is called isolated tremor, and tremor in combination with other signs is called combined tremor. Many isolated and combined tremor syndromes can be defined on the basis of commonly recurring or unique clinical symptoms and signs, including historical features (age at onset, family history, and temporal evolution) and tremor characteristics (body distribution, activation condition, associated features). Essential tremor, however defined, is simply a syndrome and not a specific disease. Essential tremor should be defined and used consistently, or this term should be abandoned. As essential tremor is an arbitrarily defined syndrome, it makes no sense to refer to other tremors as variants of essential tremor or essential tremor syndromes.
特发性震颤在临床诊断和研究中尚未得到一致的定义和应用。其他单症状性疾病常被称为特发性震颤变异型。
现在有确凿证据表明，无论如何定义，特发性震颤都是一种具有多种病因的综合征。
国际帕金森病和运动障碍协会震颤特别工作组正在制定一种新的震颤分类方案。在该方案中，无其他神经体征的震颤称为孤立性震颤，伴有其他体征的震颤称为合并性震颤。许多孤立性和合并性震颤综合征可根据常见或独特的临床症状和体征来定义，包括病史特征（发病年龄、家族史和时间演变）和震颤特征（身体分布、诱发条件、相关特征）。无论如何定义，特发性震颤都只是一种综合征而非特定疾病。应始终一致地定义和使用特发性震颤，否则应摒弃该术语。由于特发性震颤是一个任意定义的综合征，将其他震颤称为特发性震颤变异型或特发性震颤综合征是没有意义的。
