Benikova E A, Bol'shova E V
Probl Endokrinol (Mosk). 1987 Nov-Dec;33(6):25-8.
A study was made of the level of prolactin in the blood plasma of 55 patients aged 16 to 23 with different types of gonad dysgenesia. It was shown for the first time that in most of the patients with gonad dysgenesia disregarding pathology type the level of prolactin did not differ from that in the follicular phase of the menstrual cycle of healthy girls, and was significantly decreased as compared to the level of this hormone in the luteal phase. Estrogen therapy caused a considerable rise of the prolactin level in all the examines. The detection of hyperprolactinemia in patients with gonad dysgenesia can indicate a possibility of the development of microadenomas of the hyperstimulated hypophysis in them.
对55名年龄在16至23岁之间、患有不同类型性腺发育不全的患者血浆中的催乳素水平进行了研究。首次发现，在大多数性腺发育不全患者中，无论病理类型如何，催乳素水平与健康女孩月经周期卵泡期的水平无差异，且与黄体期该激素水平相比显著降低。雌激素治疗使所有受检者的催乳素水平大幅升高。性腺发育不全患者中高催乳素血症的检测可能表明他们有发生垂体过度刺激微腺瘤的可能性。
