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新西兰毛利人和非毛利肺癌患者疼痛药物获取的全国性研究。

National Study of Pain Medicine Access Among Māori and Non-Māori Patients With Lung Cancer in New Zealand.

机构信息

Department of Public Health, University of Otago, Wellington, New Zealand.

Capital and Coast District Health Board, Wellington, New Zealand.

出版信息

JCO Glob Oncol. 2021 Aug;7:1276-1285. doi: 10.1200/GO.21.00141.

Abstract

PURPOSE

Pain is among the most common and consequential symptoms of cancer, particularly in the context of lung cancer. Māori have extremely high rates of lung cancer, and there is evidence that Māori patients with lung cancer are less likely to receive curative treatment and more likely to receive palliative treatment and to wait longer for their treatment than non-Māori New Zealanders. The extent to which Māori patients with lung cancer are also less likely to have access to pain medicines as part of their supportive care remains unclear.

METHODS

Using national-level Cancer Registry and linked health records, we describe access to subsidized pain medicines among patients with lung cancer diagnosed over the decade spanning 2007-2016 and compare access between Māori and non-Māori patients. Descriptive and logistic regression methods were used to compare access between ethnic groups.

RESULTS

We observed that the majority of patients with lung cancer are accessing some form of pain medicine and there do not appear to be strong differences between Māori and non-Māori in terms of overall access or the type of pain medicine dispensed. However, Māori patients appeared more likely than non-Māori to first access pain medicines within 2 weeks before their death and commensurately less likely to access them more than 24 weeks before death.

CONCLUSION

Given the plausibility that there are differences in first access to pain medicines (particularly opioid medicines) among Māori approaching end of life, further investigation of the factors contributing to this disparity is required.

摘要

目的

疼痛是癌症最常见和最具影响的症状之一,尤其是在肺癌的情况下。毛利人患肺癌的比率极高,有证据表明,毛利肺癌患者接受根治性治疗的可能性较低,接受姑息性治疗的可能性较高,等待治疗的时间也比非毛利新西兰人长。毛利肺癌患者获得疼痛药物作为支持性治疗的机会是否也较低,目前尚不清楚。

方法

利用国家级癌症登记处和相关健康记录,我们描述了 2007 年至 2016 年期间诊断出的肺癌患者获得补贴性疼痛药物的情况,并比较了毛利人和非毛利人患者之间的获得情况。采用描述性和逻辑回归方法比较了不同种族群体之间的获得情况。

结果

我们观察到,大多数肺癌患者都在使用某种形式的止痛药,毛利人和非毛利人在总体获得情况或配给的止痛药类型方面似乎没有明显差异。然而,毛利患者比非毛利患者更有可能在死亡前 2 周内首次获得止痛药,而在死亡前 24 周以上获得止痛药的可能性相应较低。

结论

鉴于毛利人临终前首次获得止痛药(特别是阿片类药物)的可能性存在差异,需要进一步调查导致这种差异的因素。

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The impact of patient comorbidity on cancer stage at diagnosis.患者合并症对诊断时癌症分期的影响。
Br J Cancer. 2015 Nov 3;113(9):1375-80. doi: 10.1038/bjc.2015.355. Epub 2015 Oct 13.
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Clinical management of pain in advanced lung cancer.晚期肺癌的疼痛临床管理。
Clin Med Insights Oncol. 2012;6:331-46. doi: 10.4137/CMO.S8360. Epub 2012 Oct 8.
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Treatment of cancer pain.癌症疼痛的治疗。
Lancet. 2011 Jun 25;377(9784):2236-47. doi: 10.1016/S0140-6736(11)60236-5.

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