Institute of Laboratory Medicine and Pathobiochemistry, Molecular Diagnostics, Universitatsklinikum Giessen und Marburg GmbH, Giessen, Germany
J Investig Med. 2022 Jan;70(1):14-19. doi: 10.1136/jim-2020-001609. Epub 2021 Aug 12.
Multiple sclerosis (MS) is an autoimmune disorder that affects ~2.5 million people globally. Women of reproductive age are highly susceptible to this disease. This study aims to explore the association between MS and pregnancy. Articles related to the topic under investigation were identified; the search terms included "pregnancy", "multiple sclerosis", "MS", and "women". Only articles published between 2010 and 2020 were included in the review. This review shows that researchers have attempted to explore the link between pregnancy and MS, and the results from previous studies indicate that pregnancy reduces the risk of MS relapse. However, evidence suggesting that pregnancy can affect the long-term progression of MS is lacking. The research results also indicate that MS does not increase the risk of maternal and fetal complications. MS remains a serious autoimmune disorder that affects many women worldwide. The data gathered during this review indicate that a significant correlation exists between pregnancy and MS relapse rates. The findings presented in this review can aid in the management of MS during pregnancy. Furthermore, these research results provide vital insights that caregivers can use to monitor patients with MS during pregnancy.
多发性硬化症(MS)是一种自身免疫性疾病,影响着全球约 250 万人。育龄妇女极易受到这种疾病的影响。本研究旨在探讨多发性硬化症与妊娠之间的关联。确定了与研究主题相关的文章;搜索词包括“妊娠”、“多发性硬化症”、“MS”和“妇女”。本综述仅纳入了 2010 年至 2020 年期间发表的文章。本综述表明,研究人员试图探讨妊娠与多发性硬化症之间的联系,先前的研究结果表明妊娠降低了多发性硬化症复发的风险。然而,缺乏证据表明妊娠会影响多发性硬化症的长期进展。研究结果还表明,多发性硬化症并不会增加母婴并发症的风险。多发性硬化症仍然是一种严重的影响全球许多妇女的自身免疫性疾病。本综述中收集的数据表明,妊娠与多发性硬化症复发率之间存在显著相关性。本综述中提出的研究结果可以帮助管理妊娠期间的多发性硬化症。此外,这些研究结果为护理人员提供了宝贵的见解,以便在孕妇患有多发性硬化症期间对其进行监测。