Perez Neria J, Lama M S, Monteverde H R, Ocaña H, Chapela Mendoza R, Mendoza Mendoza A
Instituto Nacional de Enfermedades Respiratorias, S.S.A., Mexico, D.F.
Respiration. 1987;52(4):254-62. doi: 10.1159/000195334.
In order to find a physiological parameter which discriminates between the predominance of inflammation or fibrosis, pulmonary function tests and open lung biopsy were performed on 19 patients with interstitial lung disease. Our results showed that the only test which may be useful is the dynamic lung compliance/quasi-static lung compliance (Cdyn/Cst) index. In this context, values equal or lower than 0.85 of the Cdyn/Cst index indicate that inflammation predominates, and values higher than 0.85 suggest that interstitial fibrosis is the main feature.
为了找到一个能够区分炎症或纤维化为主的生理参数，对19例间质性肺病患者进行了肺功能测试和开胸肺活检。我们的结果表明，唯一可能有用的测试是动态肺顺应性/准静态肺顺应性（Cdyn/Cst）指数。在这种情况下，Cdyn/Cst指数等于或低于0.85表明炎症为主，而高于0.85的值表明间质性纤维化是主要特征。
