Univ Rennes, EHESP, REPERES (Recherche en pharmaco-épidémiologie et recours aux soins) - EA 7449, Rennes.
INSERM, Population-Based Epidemiological Cohorts unit, UMS 011, Villejuif.
J Hypertens. 2021 Dec 1;39(12):2497-2505. doi: 10.1097/HJH.0000000000002959.
Reducing hypertension represents a critical point of intervention to lower the burden of cardiovascular disease worldwide. Although the relationship between lower socioeconomic status and higher rates of hypertension is well documented, most of the evidence comes from prevalence studies involving young adult population.
To investigate the independent association of wealth, education and income with incident hypertension among older adults living in the United States.
This cohort study included 16 587 individuals aged 50 years and older, free of hypertension and cardiovascular disease at baseline from the Health and Retirement Study over the period 1992-2014. We used Cox proportional hazards models to examine longitudinal associations between wealth, education, and income at baseline and self-reported diagnosis of incident hypertension.
During a median follow-up of 7.8 years, 6817 participants declared an occurrence of hypertension (incidence rate: 45.3 [95% confidence interval (CI) = 44.2-46.4] per 1000 person-years). Overall, those in low as compared with high socioeconomic status groups had a higher risk of developing hypertension in late life. In particular, adjusted hazard ratios [95% CI] across decreasing wealth quartiles were 1.0 (reference), 0.97 [0.88-1.08], 1.17 [1.05-1.30], and 1.20 [1.07-1.35] in men, and 1.0 (reference), 1.28 [1.17-1.41], 1.21 [1.09-1.33], and 1.28 [1.16-1.42] in women. In multivariate analyses, wealth remained strongly associated with incident hypertension among women after accounting for other socioeconomic, behavioral and anthropometric risk factors.
Socioeconomic status, especially wealth, is a strong independent predictor of incident hypertension in older adults. Our findings support population-based interventions tailored to those in disadvantaged socioeconomic groups to reduce the risk of hypertension.
降低高血压是降低全球心血管疾病负担的一个关键干预点。尽管较低社会经济地位与高血压发病率较高之间的关系已有充分记录,但大多数证据来自于涉及年轻成年人的流行率研究。
研究美国老年人中财富、教育和收入与高血压发病之间的独立关联。
这项队列研究纳入了来自 1992 年至 2014 年期间的健康与退休研究中的 16587 名年龄在 50 岁及以上、基线时无高血压和心血管疾病的个体。我们使用 Cox 比例风险模型来检查基线时财富、教育和收入与自我报告的高血压发病之间的纵向关联。
在中位随访 7.8 年期间,有 6817 名参与者报告了高血压的发生(发病率:45.3 [95%置信区间(CI)=44.2-46.4] / 1000 人年)。总体而言,与社会经济地位较高的人群相比,社会经济地位较低的人群在晚年发生高血压的风险更高。特别是,在财富递减的四分位中,调整后的风险比(95%CI)在男性中分别为 1.0(参考)、0.97 [0.88-1.08]、1.17 [1.05-1.30]和 1.20 [1.07-1.35],在女性中分别为 1.0(参考)、1.28 [1.17-1.41]、1.21 [1.09-1.33]和 1.28 [1.16-1.42]。在多变量分析中,在考虑了其他社会经济、行为和人体测量风险因素后,财富与女性高血压发病之间仍然存在很强的关联。
社会经济地位,尤其是财富,是老年人高血压发病的一个强有力的独立预测因素。我们的研究结果支持针对社会经济弱势群体的基于人群的干预措施,以降低高血压的风险。