Department of Psychiatry, University of Alberta, Edmonton, AB, Canada.
Department of Medicine (Neurology), University of Alberta, Edmonton, AB, Canada.
Handb Clin Neurol. 2021;183:221-234. doi: 10.1016/B978-0-12-822290-4.00010-4.
Autoimmune encephalitis often produces signs and symptoms that appear to be at the interface between neurology and psychiatry. Since psychiatric symptoms are often prominent, patients are often first seen in a psychiatric setting. Therefore it is important that psychiatrists, as well as neurologists, be able to recognize autoimmune encephalitis, a task that is often difficult. Early diagnosis of autoimmune encephalitis is crucial as this will usually result in a better outcome for the patient. This chapter provides an introduction to various autoimmune encephalitides and describes their pathophysiology and the possible associated neuropsychiatric, neuropsychological (cognitive), and neurological (sensory-motor) signs and symptoms. This chapter also reviews the possible treatments of these associated signs and symptoms.
自身免疫性脑炎常产生神经科和精神科之间的症状和体征。由于精神症状通常较为突出,患者常首先在精神科就诊。因此,精神科医生和神经科医生都能够识别自身免疫性脑炎非常重要,而这通常是很困难的。早期诊断自身免疫性脑炎至关重要,因为这通常会使患者的预后更好。本章介绍了各种自身免疫性脑炎,并描述了它们的病理生理学以及可能相关的神经精神、神经心理学(认知)和神经(感觉运动)的体征和症状。本章还回顾了这些相关体征和症状的可能治疗方法。