Krannert Institute of Cardiology, Indiana University, Indianapolis, IN.
Division of Nephrology, Indiana University, Indianapolis, IN.
Adv Chronic Kidney Dis. 2021 Jan;28(1):37-46. doi: 10.1053/j.ackd.2021.01.002.
Heart failure and kidney failure are very common conditions, precipitating and exacerbating each other. Left ventricular assist devices (LVADs) represent a relatively new technology for treatment of advanced heart failure. Kidney dysfunction, if present, makes candidate selection for LVADs challenging and contributes to multiple complications while the patients are on an LVAD support. Although kidney function generally improves after LVAD implantation, some patients develop acute and then chronic kidney disease sometimes requiring kidney replacement therapies (KRTs). Overall, chronic KRT in LVAD recipients is feasible and well tolerated, but routine technique of blood pressure monitoring should be adjusted to the continuous blood flow. Both hemodialysis and peritoneal dialysis can be used. Unique challenges for chronic KRT posed by the presence of LVAD are discussed in this review.
心力衰竭和肾衰竭是非常常见的病症,会相互诱发和加重。左心室辅助装置(LVAD)是治疗晚期心力衰竭的一种相对较新的技术。如果存在肾功能障碍,会使 LVAD 候选者的选择变得具有挑战性,并在患者接受 LVAD 支持时导致多种并发症。尽管 LVAD 植入后肾功能通常会改善,但有些患者会出现急性和慢性肾脏病,有时需要肾脏替代治疗(KRT)。总的来说,LVAD 受者的慢性 KRT 是可行且耐受良好的,但应根据持续血流调整常规血压监测技术。可以使用血液透析和腹膜透析。本文综述了 LVAD 存在给慢性 KRT 带来的独特挑战。