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在翻修全膝关节置换术中,锥形和袖套具有良好的存活率和临床结果:一项荟萃分析。

Cones and sleeves present good survival and clinical outcome in revision total knee arthroplasty: a meta-analysis.

机构信息

Orthopaedic Department Waldkliniken Eisenberg, Orthopaedic Professorship of the University Hospital Jena, Klosterlausnitzer Str. 81, 07607, Eisenberg, Germany.

Department of Medical Statistics, Informatics and Data Science, Jena University Hospital Jena, Bach Str. 18, 07743, Jena, Germany.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2022 Aug;30(8):2824-2837. doi: 10.1007/s00167-021-06670-0. Epub 2021 Aug 13.

Abstract

PURPOSE

The fixation of revision total knee arthroplasties (rTKA) tends to be difficult, leading to a reduction in implant survival. One option for achieving a more stable anchorage is to use metaphyseal cones and sleeves. The objective of the present paper is to provide a current comparative meta-analysis on survival and clinical results of cones vs. sleeves, with a differentiation between the short- and long-term outcome.

METHODS

A search of the literature was conducted systematically to include original papers from 2010 to June 2021. The following parameters were taken into account: revision for aseptic loosening, revision for any reason, periprosthetic joint infections (PJI), KSS as well as KSFS. Studies with a mean follow-up of at least 60 months were defined to be long-term follow-up studies (LT). All other studies were included in the short-term (ST) study analysis. A pooled incidence was used as a summary statistic using a random intercept logistic regression model.

RESULTS

The present meta-analysis included 43 publications with 3008 rTKA. Of these, 23 publications with 1911 cases were allocated to the sleeve group (SG) and 20 papers with 1097 cases to the cone group (CG). CG showed overall numerically higher complication rates in short- and long-term follow-up, compared with SG. Aseptic loosening occurred at a rate of 0.4% in SG (LT) and 4.1% in CG (LT) (p = 0.09). Periprosthetic joint infection (PJI) was more frequent in the cone group (7% in ST and 11.7% in LT) than in the sleeve group (3.4% in ST and 4.9% in LT, p = 0.02 both). The total revision rate was 5.5% in SG (LT) and 14.4% in CG (LT) (p = 0.12). The clinical scores were also comparable between the two groups. Hinged prothesis were used more frequent in the cone group (ST p < 0.001; LT p = 0.10), whereas CC type protheses were used more frequently in the sleeve group (ST p < 0.001; LT p < 0.11).

CONCLUSIONS

This meta-analysis takes into account the longest follow-up periods covered to date. Both cones and sleeves represent a reliable fixation method in the case of severe bone loss in rTKA, although the higher rate of PJI after cone fixation remains a source of concern. A metaphyseal fixation of hinged implants should be taken into account.

LEVEL OF EVIDENCE

II (meta-analysis).

摘要

目的

翻修全膝关节置换术(rTKA)的固定往往较为困难,导致植入物的存活率降低。一种更稳定的固定方法是使用骨水泥型胫骨假体。本文的目的是提供一个目前关于胫骨假体和套管的生存和临床结果的荟萃分析,并对短期和长期结果进行区分。

方法

系统地对文献进行了检索,纳入了 2010 年至 2021 年 6 月的原始论文。考虑了以下参数:无菌性松动翻修、任何原因翻修、假体周围关节感染(PJI)、KSS 和 KSFS。平均随访至少 60 个月的研究被定义为长期随访研究(LT)。其他所有研究均纳入短期(ST)研究分析。使用随机截距逻辑回归模型作为汇总统计量的合并发生率。

结果

本荟萃分析纳入了 43 项研究,涉及 3008 例 rTKA。其中,23 项研究涉及 1911 例患者被分配到套管组(SG),20 项研究涉及 1097 例患者被分配到锥体组(CG)。与 SG 相比,CG 在短期和长期随访中总体上显示出更高的并发症发生率。SG 的无菌性松动发生率为 0.4%(LT),CG 的无菌性松动发生率为 4.1%(LT)(p=0.09)。CG 的假体周围关节感染(PJI)发生率高于 SG(ST 为 7%,LT 为 11.7%)(p=0.02)。SG 的总翻修率为 5.5%(LT),CG 的总翻修率为 14.4%(LT)(p=0.12)。两组的临床评分也相似。CG 中更频繁使用铰链假体(ST p<0.001;LT p=0.10),而 SG 中更频繁使用 CC 型假体(ST p<0.001;LT p<0.11)。

结论

本荟萃分析考虑了迄今为止最长的随访期。在 rTKA 严重骨丢失的情况下,胫骨假体和套管均代表一种可靠的固定方法,尽管锥体固定后 PJI 发生率较高仍是一个令人关注的问题。应考虑使用铰链植入物的骨干固定。

证据水平

II 级(荟萃分析)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9568/9309140/e16f3f92557a/167_2021_6670_Fig1_HTML.jpg

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