Bŭrdarov I, Savova-Bŭrdarova S
Vet Med Nauki. 1987;24(8):23-7.
The seasonal dynamics of the meningoencephalitic form of listeriosis in lambs was followed up. The peak values in the disease course were found to be in the months of February and March. It is likely that outbreaks coincide with the start in feeding the lambs with roughage. The disease was bacteriologically and histologically shown to run its course primarily in lambs aged up to 6 months. Only in 3 cases the affected lambs were up to ten days of age. The changes in the central nervous system were characterized by leukocytic infiltration and diffuse glial proliferation (in 60.2 per cent of the cases), while in adult sheep predominated the focal glial proliferation. Liver and kidney cells showed necrobiotic changes. The use of the method of antibiotic prophylaxis led to recurrence of the disease, while immunizations with an inactivated vaccine against listeriosis suppressed further outbreaks.
对羔羊李斯特菌病脑膜脑炎型的季节性动态进行了跟踪。病程中的峰值出现在2月和3月。疫情爆发可能与开始用粗饲料喂养羔羊的时间相吻合。细菌学和组织学研究表明，该病主要发生在6个月龄以下的羔羊中。仅3例受影响的羔羊年龄在10日龄以下。中枢神经系统的变化特征为白细胞浸润和弥漫性胶质细胞增生（占病例的60.2%），而成年绵羊中则以局灶性胶质细胞增生为主。肝和肾细胞出现坏死性变化。使用抗生素预防方法导致疾病复发，而用灭活李斯特菌疫苗进行免疫可抑制进一步的疫情爆发。
