College of Nursing·Research Institute of Nursing Science, Ajou University, 164, World cup-Ro, Yeongtong-Gu, Suwon, 16499, Korea.
Department of Cardiology, Ajou University Medical Center, Suwon, South Korea.
Health Qual Life Outcomes. 2021 Aug 14;19(1):196. doi: 10.1186/s12955-021-01832-7.
Myocardial infarction and unstable angina are prevalent in Korea. The MacNew Heart Disease health-related quality of life questionnaire is a widely used patient-reported outcome measure for patients with heart disease in several countries. In this study, we tested the validity and reliability of the Korean version of the MacNew (K-MacNew).
Participants were 200 patients who had experienced unstable angina or myocardial infarction, and were recruited from a tertiary hospital in Korea. The K-MacNew was developed using forward-backward translation techniques. Construct validity (including discriminative validity), concurrent validity, and internal consistency reliability of the K-MacNew were assessed. Discriminative validity was assessed by examining the between-group differences in the K-MacNew scores according to functional capacity, anxiety, and depression levels. Concurrent validity was examined by correlating the K-MacNew dimensions with the physical and mental health domains of the 36-item Short Form Health Survey Instrument (SF-36).
Factor analysis results of the K-MacNew demonstrated a three-factor structure (emotional, physical, and social) that explained 57.92% of the variance. Significant differences in the K-MacNew scores were observed according to patients' functional capacity, anxiety, and depression levels. The SF-36 physical health domain score showed a moderate positive correlation with the physical dimension score of the K-MacNew (r = 0.517, P < 0.001), and the SF-36 mental health domain score showed a strong positive correlation with the emotional dimension of K-MacNew (r = 0.745, P < 0.001). The K-MacNew showed good internal consistency, with a Cronbach's α of 0.947 for the global scale.
The K-MacNew demonstrated good reliability and validity for use as a patient-reported outcome measure and is ready for the assessment of the health-related quality of life of patients with coronary artery disease in Korea. To establish the clinical validity of the K-MacNew, additional studies should be conducted to verify the validity and reliability of the K-MacNew in a number of participants, including those with various types of coronary artery disease.
心肌梗死和不稳定型心绞痛在韩国较为常见。MacNew 心脏疾病健康相关生活质量问卷是一种广泛应用于多个国家心脏病患者的患者报告结局测量工具。本研究旨在检验韩文版 MacNew(K-MacNew)的效度和信度。
本研究共纳入 200 例曾经历不稳定型心绞痛或心肌梗死的患者,均来自韩国的一家三级医院。采用正向-反向翻译技术制定 K-MacNew。评估 K-MacNew 的结构效度(包括区分效度)、同时效度和内部一致性信度。通过比较 K-MacNew 评分在患者功能能力、焦虑和抑郁水平方面的组间差异来评估区分效度。通过将 K-MacNew 各维度与 36 项简明健康调查问卷(SF-36)的身体和精神健康领域相关联来评估同时效度。
K-MacNew 的因子分析结果显示,三因素结构(情绪、身体和社会)可解释 57.92%的方差。K-MacNew 评分在患者的功能能力、焦虑和抑郁水平方面存在显著差异。SF-36 身体健康领域评分与 K-MacNew 的身体维度评分呈中度正相关(r=0.517,P<0.001),SF-36 心理健康领域评分与 K-MacNew 的情绪维度评分呈强正相关(r=0.745,P<0.001)。K-MacNew 具有良好的内部一致性,总量表的 Cronbach's α 为 0.947。
K-MacNew 作为一种患者报告结局测量工具具有良好的信度和效度,可用于评估韩国冠状动脉疾病患者的健康相关生活质量。为了确立 K-MacNew 的临床有效性,应在更多的参与者中进一步开展研究,以验证 K-MacNew 的效度和信度,包括各种类型的冠状动脉疾病患者。