具有败血症和肺炎临床表现的大疱性表皮松解症：一例报告

Epidermolysis bullosa with clinical manifestations of sepsis and pneumonia: A case report.

作者信息

Khanmohammadi Samira, Yousefzadeh Raheleh, Rashidan Maryam, Hajibeglo Azam, Bekmaz Karvan

机构信息

Department of Nursing, Ali Abad Katoul Branch, Islamic Azad University, Ali Abad Katoul, Iran.

MSC in Geriatric Nursing, Department of Nursing and Midwifery, Bojnurd University Medical Science. Khorasan Somali, Iran.

出版信息

Int J Surg Case Rep. 2021 Sep;86:106258. doi: 10.1016/j.ijscr.2021.106258. Epub 2021 Jul 31.

DOI:10.1016/j.ijscr.2021.106258

PMID:34392018

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8371221/

Abstract

BACKGROUND

Epidermolysis bullosa is an inherited disease that causes bleeding blisters on the skin tissues and mucosal membranes. This study reports a case of epidermolysis bullosa with clinical manifestations of sepsis and pneumonia.

CASE REPORT

A 17-month-old female with epidermolysis bullosa presented with clinical manifestations of sepsis and pneumonia, including increased body temperature, anorexia, and wheezing. Blood test results included the following: white blood cell (WBC) count, 24,000/μl; hemoglobin level, 7.9 mg/dl; erythrocyte sedimentation rate (ESR), 99 mm/h; and C-reactive protein level, +2. The patient was given ceftriaxone, vancomycin, hydrocortisone, and acetaminophen. The patient's fever resolved on the third day of hospitalization, and the ESR and WBC count reached 25 mm/h and 9900/μl, respectively.

CONCLUSIONS

According to the report, it is recommended to consider an increase in body temperature, WBC count, and ESR, and perform the required attempts in patients with epidermolysis bullosa.

摘要

背景

大疱性表皮松解症是一种遗传性疾病，可导致皮肤组织和粘膜出现出血性水疱。本研究报告了一例伴有败血症和肺炎临床表现的大疱性表皮松解症病例。

病例报告

一名17个月大患有大疱性表皮松解症的女性出现败血症和肺炎的临床表现，包括体温升高、厌食和喘息。血液检查结果如下：白细胞（WBC）计数为24,000/μl；血红蛋白水平为7.9mg/dl；红细胞沉降率（ESR）为99mm/h；C反应蛋白水平为+2。给予患者头孢曲松、万古霉素、氢化可的松和对乙酰氨基酚。患者在住院第三天体温恢复正常，ESR和WBC计数分别达到25mm/h和9900/μl。