Department of Anaesthesiology, Aarhus University Hospital, Palle Juul Jensens Boulevard, Aarhus N DK-8200, Denmark.
Anesthesiol Clin. 2021 Sep;39(3):525-535. doi: 10.1016/j.anclin.2021.03.010.
The main goal of perioperative coagulation monitoring is to improve safety of patients undergoing surgical procedures. Various conditions can affect the coagulation system during surgery and bleeding. The value of traditional standard coagulation tests is limited in detecting hemostatic dysfunctions and they are particularly ineffective in diagnosing hyperfibrinolysis. This article reports on key issues and pathophysiologic changes that affect the hemostatic system in the perioperative setting. Values of preoperative coagulation tests are discussed and the basic principles for point-of-care coagulation devices, including platelet analyzers and their clinical use, are evaluated.
围手术期凝血监测的主要目标是提高接受手术治疗的患者的安全性。各种情况都会影响手术期间和出血时的凝血系统。传统标准凝血检测在检测止血功能障碍方面的价值有限，在诊断纤维蛋白溶解亢进方面尤其无效。本文报告了影响围手术期止血系统的关键问题和病理生理变化。讨论了术前凝血检测的价值，并评估了即时检测凝血设备（包括血小板分析仪及其临床应用）的基本原理。
