Jinnouchi Takanobu, Sakurai Yoshitaka, Miyoshi Kengo, Koizumi Chie, Waki Hironori, Kubota Naoto, Yamauchi Toshimasa
Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Japan.
Department of Clinical Nutrition Therapy, The University of Tokyo, Japan.
Intern Med. 2022 Feb 15;61(4):469-474. doi: 10.2169/internalmedicine.7714-21. Epub 2021 Aug 13.
Chronic intestinal pseudo-obstruction (CIPO) is a rare disorder of intestinal dysmotility characterized by chronic symptoms, including vomiting and abdominal pain, associated with bowel obstruction without any mechanical obstructive causes. We herein report a case of mitochondrial diseases with recurrent duodenal obstruction that was initially diagnosed as superior mesenteric artery syndrome (SMAS) for a few years but was later diagnosed as CIPO. Since CIPO is known to be associated with mitochondrial diseases, it should be considered in the differential diagnosis of patients with mitochondrial diseases presenting with recurrent intestinal obstruction.
慢性假性肠梗阻（CIPO）是一种罕见的肠道动力障碍性疾病，其特征为慢性症状，包括呕吐和腹痛，伴有肠梗阻但无任何机械性梗阻原因。我们在此报告一例线粒体疾病伴复发性十二指肠梗阻的病例，该病例最初被诊断为肠系膜上动脉综合征（SMAS）数年，但后来被诊断为CIPO。由于已知CIPO与线粒体疾病有关，因此在对出现复发性肠梗阻的线粒体疾病患者进行鉴别诊断时应考虑到这一点。
