Turi A, Di Prospero F, Mazzarini A, Ceschini E, Romanini C, Campanari G, Foschi F
Università degli Studi di Ancona, Istituto di Clinica Ostetrica e Ginecologica.
Acta Eur Fertil. 1987 May-Jun;18(3):193-5.
In 35 women, 16-32 years old (average age 24) affected by hirsutism associated to menstrual disorders as oligomenorrhea or secondary amenorrhea, the real utility of testosterone's free fraction assay (FT) in comparison with conventional hormonal assays has been valued. The free testosterone (FT) resulted the most frequently elevated hormone (69%). The analysis of the different groups shows a good sensitivity and specificity of FT assay in some conditions as PCOD, but it is not so sensitive and specific in other conditions as secondary amenorrhea. We conclude that FT assay is particularly useful for the hyperandrogenism study, especially in the PCOD; for its high diagnostic sensitivity it would be assayed in all the women with hirsutism, but it isn't sufficient for the screening of the different hyperandrogenic states.
在35名年龄在16至32岁（平均年龄24岁）、患有多毛症且伴有月经紊乱（如月经过少或继发性闭经）的女性中，对游离睾酮测定（FT）与传统激素测定相比的实际效用进行了评估。游离睾酮（FT）是最常升高的激素（69%）。对不同组别的分析表明，FT测定在某些情况下（如多囊卵巢综合征）具有良好的敏感性和特异性，但在其他情况下（如继发性闭经）则并非如此敏感和特异。我们得出结论，FT测定对于高雄激素血症的研究特别有用，尤其是在多囊卵巢综合征中；由于其高诊断敏感性，应在所有多毛症女性中进行检测，但它不足以筛查不同的高雄激素状态。
