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Optimising medicines use in older adults with intellectual disability who have epilepsy: challenges and perspectives.优化患有癫痫的智障老年人的药物使用：挑战与展望。
Ther Adv Drug Saf. 2021 Aug 4;12:20420986211025157. doi: 10.1177/20420986211025157. eCollection 2021.
2
Prevalence and patterns of anti-epileptic medication prescribing in the treatment of epilepsy in older adults with intellectual disabilities.老年智力障碍癫痫患者抗癫痫药物治疗的流行情况和模式。
J Intellect Disabil Res. 2018 Mar;62(3):245-261. doi: 10.1111/jir.12461. Epub 2018 Jan 5.
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Central nervous system medication use in older adults with intellectual disability: Results from the successful ageing in intellectual disability study.智障老年人的中枢神经系统药物使用情况：智障者成功老龄化研究的结果
Aust N Z J Psychiatry. 2016 Apr;50(4):352-62. doi: 10.1177/0004867415587951. Epub 2015 May 27.
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Effects of music on seizure frequency in institutionalized subjects with severe/profound intellectual disability and drug-resistant epilepsy.音乐对患有严重/极重度智力残疾和耐药性癫痫的机构化受试者癫痫发作频率的影响。
Psychiatr Danub. 2017 Sep;29(Suppl 3):399-404.
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Prevalence, patterns and factors associated with psychotropic use in older adults with intellectual disabilities in Ireland.爱尔兰智障老年人群体中心理治疗类药物的使用现状、模式及相关因素分析。
J Intellect Disabil Res. 2017 Oct;61(10):969-983. doi: 10.1111/jir.12391. Epub 2017 Jun 21.
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Ambiguous results of an attempt to withdraw barbiturates in epilepsy patients with intellectual disability.在智力残疾癫痫患者中尝试停用巴比妥类药物的结果不明确。
Seizure. 2009 Mar;18(2):109-18. doi: 10.1016/j.seizure.2008.07.006. Epub 2008 Aug 29.
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Quality improvement in the management of people with epilepsy and intellectual disability: the development of clinical guidance.改善癫痫合并智力障碍患者管理质量：临床指南的制定。
Expert Opin Pharmacother. 2020 Feb;21(2):173-181. doi: 10.1080/14656566.2019.1695780. Epub 2019 Nov 30.
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Prevalence of Pathogenic Copy Number Variation in Adults With Pediatric-Onset Epilepsy and Intellectual Disability.患有儿童期起病癫痫和智力障碍的成人中致病性拷贝数变异的患病率
JAMA Neurol. 2017 Nov 1;74(11):1301-1311. doi: 10.1001/jamaneurol.2017.1775.
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Measuring drug burden in older adults with intellectual disabilities: Critical issues for consideration in finding the optimal measure to improve safety of medicines use.测量智障老年人的药物负担：寻找最佳测量方法以提高用药安全性时需考虑的关键问题。
Expert Opin Drug Saf. 2020 Jun;19(6):649-652. doi: 10.1080/14740338.2020.1751119. Epub 2020 Apr 13.
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The phenotypic spectrum of ARHGEF9 includes intellectual disability, focal epilepsy and febrile seizures.ARHGEF9的表型谱包括智力残疾、局灶性癫痫和热性惊厥。
J Neurol. 2017 Jul;264(7):1421-1425. doi: 10.1007/s00415-017-8539-3. Epub 2017 Jun 15.

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1
The relationship between clinical presentation and the nature of care in adults with intellectual disability and epilepsy - national comparative cohort study.成年智力残疾和癫痫患者的临床表现与护理性质之间的关系——全国性比较队列研究
BJPsych Open. 2024 Apr 30;10(3):e94. doi: 10.1192/bjo.2024.45.
2
Rapid switching from levetiracetam to brivaracetam in pharmaco-resistant epilepsy in people with and without intellectual disabilities: a naturalistic case control study.在伴有和不伴有智力障碍的药物难治性癫痫患者中，从左乙拉西坦快速转换为布瓦西坦：一项自然病例对照研究。
J Neurol. 2023 Dec;270(12):5889-5902. doi: 10.1007/s00415-023-11959-w. Epub 2023 Aug 23.

本文引用的文献

1
Best care for older people with epilepsy: A scoping review.老年人癫痫最佳护理：范围综述。
Seizure. 2021 Feb;85:70-89. doi: 10.1016/j.seizure.2020.12.007. Epub 2021 Jan 13.
2
Eslicarbazepine acetate response in intellectual disability population versus general population.与普通人群相比，智力残疾人群对醋酸艾司利卡西平的反应。
Acta Neurol Scand. 2021 Mar;143(3):256-260. doi: 10.1111/ane.13368. Epub 2020 Nov 24.
3
Association between epilepsy and challenging behaviour in adults with intellectual disabilities: systematic review and meta-analysis.智力残疾成年人癫痫与挑战性行为之间的关联：系统评价与荟萃分析
BJPsych Open. 2020 Sep 25;6(5):e114. doi: 10.1192/bjo.2020.96.
4
Epilepsy, an orphan disorder within the neurodevelopmental family.癫痫，神经发育疾病范畴内的一种罕见病。
J Neurol Neurosurg Psychiatry. 2020 Dec;91(12):1245-1247. doi: 10.1136/jnnp-2020-324660. Epub 2020 Sep 14.
5
European perspective of perampanel response in people with Intellectual Disability.欧洲视角下智力障碍患者使用吡仑帕奈的反应。
Acta Neurol Scand. 2020 Sep;142(3):255-259. doi: 10.1111/ane.13261. Epub 2020 May 26.
6
Lacosamide in the general population and in people with intellectual disability: Similar responses?拉科酰胺在普通人群和智障人群中的反应是否相似？
Seizure. 2020 Feb 19;76:161-166. doi: 10.1016/j.seizure.2020.02.013.
7
New anti-seizure medication for elderly epileptic patients.用于老年癫痫患者的新型抗癫痫药物。
Expert Opin Pharmacother. 2019 Sep;20(13):1601-1608. doi: 10.1080/14656566.2019.1618272. Epub 2019 May 21.
8
Quantitative examination of the bone health status of older adults with intellectual and developmental disability in Ireland: a cross-sectional nationwide study.爱尔兰智障和发育障碍老年患者骨健康状况的定量检查：一项全国性横断面研究。
BMJ Open. 2019 Apr 15;9(4):e026939. doi: 10.1136/bmjopen-2018-026939.
9
Vitamin D, bone mineral density and risk of fracture in people with intellectual disabilities.维生素D、骨矿物质密度与智力残疾者的骨折风险
J Intellect Disabil Res. 2019 Apr;63(4):357-367. doi: 10.1111/jir.12581. Epub 2018 Dec 19.
10
Improving knowledge of psychotropic prescribing in people with Intellectual Disability in primary care.提高初级保健中智障患者精神药物处方知识。
PLoS One. 2018 Sep 14;13(9):e0204178. doi: 10.1371/journal.pone.0204178. eCollection 2018.

Optimising medicines use in older adults with intellectual disability who have epilepsy: challenges and perspectives.

作者信息

O'Dwyer Maire, Watkins Lance, McCallion Philip, McCarron Mary, Henman Martin, Shankar Rohit

机构信息

School of Pharmacy and Pharmaceutical Sciences, University of Dublin Trinity College, Dublin, 2, Ireland.

Swansea Bay University Health Board Ringgold Standard Institution, Neath Port Talbot, UK.

出版信息

Ther Adv Drug Saf. 2021 Aug 4;12:20420986211025157. doi: 10.1177/20420986211025157. eCollection 2021.

DOI:10.1177/20420986211025157
PMID:34394909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8361510/
Abstract
摘要