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尿毒症患儿的高脂血症:对腹膜透析和血液透析的反应

Hyperlipidemia in uremic children: response to peritoneal dialysis and hemodialysis.

作者信息

Berger M, James G P, Davis E R, Jasper P M, Brouhard B H, Travis L B, Cunningham R J

出版信息

Clin Nephrol. 1978 Jan;9(1):19-24.

PMID:343952
Abstract

Hemodialysis and hyperlipidemia have been associated in both adults and children. The present study indicates hyperlipidemia in uremic children treated with peritoneal dialysis and implies that the cardiovascular risk felt to exist with hemodialysis also exists in peritoneal dialysis. Thirty-eight children with chronic renal insufficiency or end-stage renal disease were followed serially under varying conditions of medical management, hemodialysis, peritoneal dialysis, and transplantation. Serum triglyceride concentrations in patients on peritoneal dialysis were not significantly different from those in patients on hemodialysis, but both were significantly higher (P less than 0.01) than concentrations in patients on medical management and transplantation.

摘要

血液透析和高脂血症在成人和儿童中均有关联。本研究表明接受腹膜透析治疗的尿毒症儿童存在高脂血症,这意味着血液透析中被认为存在的心血管风险在腹膜透析中同样存在。38名患有慢性肾功能不全或终末期肾病的儿童在不同的医疗管理条件下接受了连续随访,这些条件包括血液透析、腹膜透析和移植。接受腹膜透析的患者血清甘油三酯浓度与接受血液透析的患者无显著差异,但两者均显著高于(P小于0.01)接受医疗管理和移植的患者的浓度。

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