Drs. Kara and Çaliş are from Koru Hospital, Ankara, Turkey. Dr. Kara is from the Department of Dermatology, and Dr. Çaliş is from the Department of Ophthalmology. Dr. Gürel is from the Department of Ophthalmology, 29 Mayıs State Hospital, Ankara.
Cutis. 2021 Jul;108(1):46-50. doi: 10.12788/cutis.0289.
Rosacea is a chronic progressive disease that causes inflammation on the skin and the ocular surface. This study aimed to evaluate the effects of Demodex mites on clinical findings associated with rosacea. Sixty patients who were newly diagnosed with rosacea in the dermatology outpatient clinic underwent superficial skin biopsy to determine the density of Demodex species. The patients were evaluated as Demodex positive (n=30) or Demodex negative (n=30) based on the species density. The 60 patients were examined in the ophthalmology outpatient clinic; a total of 120 eyes underwent tear breakup time (TBUT) and Schirmer tests and were examined for meibomitis and blepharitis findings. The demographic characteristics and ocular findings of both groups were recorded and statistically compared. We found that Demodex mite-related inflammation in rosacea does not significantly affect clinical ocular surface findings and that Demodex positivity is significantly associated with papulopustular rosacea (PPR)(P=.003).
酒渣鼻是一种慢性进行性疾病，可导致皮肤和眼表面炎症。本研究旨在评估蠕形螨对酒渣鼻相关临床发现的影响。在皮肤科门诊新诊断为酒渣鼻的 60 名患者接受了浅层皮肤活检，以确定蠕形螨种密度。根据物种密度，患者被评估为蠕形螨阳性（n=30）或蠕形螨阴性（n=30）。60 名患者在眼科门诊进行了检查；共有 120 只眼睛进行了泪膜破裂时间（TBUT）和 Schirmer 试验，并检查了睑板腺炎和睑缘炎的发现。记录并统计比较了两组的人口统计学特征和眼部发现。我们发现酒渣鼻中与蠕形螨相关的炎症不会显著影响临床眼表面发现，并且蠕形螨阳性与丘疹脓疱性酒渣鼻（PPR）显著相关（P=.003）。
