柳氮磺胺吡啶诱导的中毒性表皮坏死松解症：COVID-19 大流行期间的一个挑战性病例。
Sulfasalazine-Induced Toxic Epidermal Necrolysis: A Challenging Case During the COVID-19 Pandemic.
机构信息
Skin Research Center (Drs Shahidi-Dadras and Dadkhahfar), Men's Health and Reproductive Health Research Center (Dr Fatemi), Department of Radiology (Dr Mahboubi-Fooladi), Department of Internal Medicine, Clinical Research Development Unit of Shohada-e-Tahrish Hospital (Dr Yazdi), Shahid Beheshti University of Medical Sciences, Tehran, Iran; and Faculty of Medicine, Université Laval, Quebec City, Quebec, Canada (Ms Shahrigharahkoshan).
出版信息
Adv Emerg Nurs J. 2021;43(3):194-197. doi: 10.1097/TME.0000000000000361.
COVID-19 is a major health issue, and patients with underlying conditions are more susceptible to catastrophic outcomes. Toxic epidermal necrolysis (TEN) is a severe systemic disease caused by an immune system hypersensitive reaction. We present a case of TEN induced following sulfasalazine administration that later on complicated with COVID-19, deep vein thrombosis, pulmonary emboli, and eventually death.
COVID-19 是一个主要的健康问题，有基础疾病的患者更容易发生灾难性的后果。中毒性表皮坏死松解症（TEN）是一种由免疫系统过敏反应引起的严重全身性疾病。我们报告了一例磺胺吡啶治疗后发生 TEN 的病例，随后并发 COVID-19、深静脉血栓形成、肺栓塞，最终死亡。
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