PET/CT Center, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing, Zhejiang Province, China.
Department of Pathology, Shaoxing People's Hospital (Shaoxing Hospital, Zhejiang University School of Medicine), Shaoxing, Zhejiang Province, China.
Medicine (Baltimore). 2021 Aug 13;100(32):e26906. doi: 10.1097/MD.0000000000026906.
Mucinous cystadenoma is a benign tumor that is commonly found in the pancreas, ovaries, or appendix, but is rarely encountered in the lungs. Worldwide, only a few reported cases of these tumors originate in the lungs. Herein, we analyzed the imaging features of a case of pulmonary mucinous cystadenoma (PMCA). To the best of our knowledge, this is the first reported case of PMCA complicated by significant infection.
A 57-year-old man was admitted to our hospital with blood in sputum for more than 2 months. Serum laboratory examination showed significantly elevated leukocyte and tumor marker, carcinoembryonic antigen. Enhanced thoracic computed tomography and whole-body positron emission tomography/computed tomography showed a cystic-solid ill-defined mass in the right upper lung.
The tumor was considered malignant, both clinically and radiologically.
The patient underwent right upper lobe tumor resection and mediastinal lymph node dissection.
Postoperative specimen pathology was diagnosed as PMCA with infection. The patient was not administered any further treatment. The patient was alive without any recurrence or metastasis of the tumor after 2 years of follow-up.
Preoperative diagnosis of PMCA with atypical imaging and clinical manifestations is extremely difficult. This is the first reported case of PMCA complicated by a significant infection that was misdiagnosed preoperatively as a malignancy.
黏液性囊腺瘤是一种常见于胰腺、卵巢或阑尾的良性肿瘤,但在肺部很少见。在全球范围内,仅有少数几例此类肿瘤起源于肺部的报道。在此,我们分析了 1 例肺黏液性囊腺瘤(PMCA)的影像学特征。据我们所知,这是首例报道的 PMCA 合并严重感染的病例。
一名 57 岁男性因痰中带血超过 2 个月而入院。血清实验室检查显示白细胞和肿瘤标志物癌胚抗原显著升高。增强胸部 CT 和全身正电子发射断层扫描/CT 显示右上肺有囊实性边界不清的肿块。
肿瘤在临床和影像学上均被认为是恶性的。
患者接受右上肺叶肿瘤切除术和纵隔淋巴结清扫术。
术后标本病理诊断为感染性 PMCA。患者未接受进一步治疗。随访 2 年后,患者无肿瘤复发或转移,仍存活。
术前诊断具有非典型影像学和临床表现的 PMCA 极其困难。这是首例报道的 PMCA 合并严重感染的病例,术前误诊为恶性肿瘤。