Theophylline and antipyrine disposition in smoking and non-smoking epileptic subjects.
作者信息
Acheson D W, Uden S, Braganza J M, Brown S W, Houston J B
机构信息
University Department of Gastroenterology, Manchester Royal Infirmary.
出版信息
Br J Clin Pharmacol. 1987 Dec;24(6):812-5. doi: 10.1111/j.1365-2125.1987.tb03250.x.
Abstract
Theophylline and antipyrine disposition has been compared in smoking epileptic patients, non-smoking epileptic patients and non-smoking healthy volunteers. Although clear differences in drug clearance and half-life were evident as a result of anticonvulsant drug therapy, no effect of smoking was discernible. Thus, additive effects from induction of the hepatic microsomal monooxygenase system in man by anticonvulsant drugs and polycyclic aromatic hydrocarbons (in cigarette smoke) were not evident.
摘要
相似文献
1
Theophylline and antipyrine disposition in smoking and non-smoking epileptic subjects.
Br J Clin Pharmacol. 1987 Dec;24(6):812-5. doi: 10.1111/j.1365-2125.1987.tb03250.x.
2
Substrate-selective inhibition by verapamil and diltiazem: differential disposition of antipyrine and theophylline in humans.
J Pharmacol Exp Ther. 1988 Mar;244(3):994-9.
3
Effect of nifedipine on antipyrine and theophylline disposition.
Biopharm Drug Dispos. 1990 Mar;11(2):157-64. doi: 10.1002/bdd.2510110208.
4
Factors contributing to the accelerated clearance of theophylline and antipyrine in adults with exocrine pancreatic disease.
Clin Sci (Lond). 1989 Apr;76(4):377-85. doi: 10.1042/cs0760377.
5
The relationship between phenazone (antipyrine) metabolite formation and theophylline metabolism in healthy and frail elderly women.
Clin Pharmacokinet. 1993 Aug;25(2):136-44. doi: 10.2165/00003088-199325020-00006.
6
The effect of acute withdrawal from cigarette smoking on indocyanine green and antipyrine clearance.
J Clin Pharmacol. 1987 Mar;27(3):226-32. doi: 10.1002/j.1552-4604.1987.tb02190.x.
7
The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of cigarette smoking on human hepatic drug metabolism.
Xenobiotica. 1990 May;20(5):537-47. doi: 10.3109/00498259009046868.
8
Large theophylline requirements due to high theophylline clearance: verification by the antipyrine test.
Pharmacology. 1986;32(4):226-31. doi: 10.1159/000138173.
9
Differential effect of cigarette smoking on antipyrine oxidation versus acetaminophen conjugation.
Pharmacology. 1990;40(2):77-84. doi: 10.1159/000138644.
10
Salivary antipyrine kinetics in hepatic and renal disease and in patients on anticonvulsant therapy.
Aust N Z J Med. 1977 Aug;7(4):385-90. doi: 10.1111/j.1445-5994.1977.tb04401.x.
引用本文的文献
1
Toward an animal model of chronic pancreatitis. Pancreatobiliary secretion in hamsters on long-term treatment with chemical inducers of cytochromes P450.
Int J Pancreatol. 1995 Oct;18(2):117-26. doi: 10.1007/BF02785885.
本文引用的文献
1
Cigarette smoking and theophylline clearance and metabolism.
Clin Pharmacol Ther. 1981 Oct;30(4):491-6. doi: 10.1038/clpt.1981.193.
2
Phenytoin-theophylline interaction.
N Engl J Med. 1982 Nov 4;307(19):1189-90. doi: 10.1056/NEJM198211043071906.
3
Differential effects of cimetidine on theophylline metabolic pathways.
Eur J Clin Pharmacol. 1984;26(3):335-40. doi: 10.1007/BF00548764.
4
Effects of tobacco smoking and oral contraceptive use on theophylline disposition.
Br J Clin Pharmacol. 1983 Sep;16(3):271-80. doi: 10.1111/j.1365-2125.1983.tb02161.x.
5
A comparative study of the relative enzyme inducing properties of anticonvulsant drugs in epileptic patients.
Br J Clin Pharmacol. 1984 Sep;18(3):401-10. doi: 10.1111/j.1365-2125.1984.tb02482.x.
6
Pharmacokinetic drug interactions with theophylline.
Clin Pharmacokinet. 1984 Jul-Aug;9(4):309-34. doi: 10.2165/00003088-198409040-00002.
7
Clinical implications of enzyme induction and enzyme inhibition.
Clin Pharmacokinet. 1981 Jan-Feb;6(1):1-24. doi: 10.2165/00003088-198106010-00001.
8
9
Antipyrine metabolite kinetics in healthy human volunteers during multiple dosing of phenytoin and carbamazepine.
Br J Clin Pharmacol. 1985 Dec;20(6):611-8. doi: 10.1111/j.1365-2125.1985.tb05119.x.
10
Induction of cytochromes P-450 in pancreatic disease: consequence, coincidence or cause?
Clin Chim Acta. 1985 Dec 13;153(2):73-84. doi: 10.1016/0009-8981(85)90158-5.
Zotero 插件