Yang Ellen, Li Tianyang, Katz Ariel
Chicago Medical School, Rosalind Franklin University of Medicine and Science, North Chicago, 60064, IL, USA.
Department of Thoracic Surgery, Jinzhou Central Hospital, Liaoning, 121000, China.
Respir Med Case Rep. 2021 May 1;33:101419. doi: 10.1016/j.rmcr.2021.101419. eCollection 2021.
Giant cell tumors of the bone are generally benign tumors of the bone, though they can be locally invasive in nature. They are also known as "osteoclastomas," and patients are typically between 20 and 40 years of age, who present with pain and swelling of the joints. Though the tumor is benign, malignant degeneration, metastasis, and other complications of tumor growth are possible. Here we present a case where a delay in treatment led to a significant tumor burden. This tumor's unique location in the anterior arc of the rib, as well as its growth to a size that has rarely been reported, ultimately caused major compressive effects that significantly impacted our patient's quality of life.
骨巨细胞瘤通常是骨的良性肿瘤,但其本质上具有局部侵袭性。它们也被称为“破骨细胞瘤”,患者通常年龄在20至40岁之间,表现为关节疼痛和肿胀。尽管该肿瘤是良性的,但仍有可能发生恶性变、转移以及肿瘤生长的其他并发症。在此我们报告一例因治疗延迟导致肿瘤负荷显著增加的病例。该肿瘤在肋骨前弧的独特位置,以及其生长到极少报道的大小,最终造成了严重的压迫效应,对我们患者的生活质量产生了重大影响。