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移民、种族与二级心脏预防治疗的依从性:ISLAND试验的一项子研究

Immigrants, Ethnicity, and Adherence to Secondary Cardiac Prevention Therapy: A Substudy of the ISLAND Trial.

作者信息

Shepherd Shaun, Ivers Noah, Natarajan Madhu K, Grimshaw Jeremy, Taljaard Monica, Bouck Zachary, Schwalm J D

机构信息

Department of Health Research Methods, Evidence, & Impact, McMaster University, Hamilton, Ontario, Canada.

Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.

出版信息

CJC Open. 2021 Mar 26;3(7):913-923. doi: 10.1016/j.cjco.2021.03.003. eCollection 2021 Jul.

Abstract

BACKGROUND

The objective of this study was to evaluate adherence to guideline-recommended cardiac secondary prevention therapies by immigration and ethnicity.

METHODS

We conducted a retrospective substudy of the nterventions upporting ong-Term dherence and ecreasing Cardiovascular Events (ISLAND) randomized controlled trial. A cohort of 1642 participants was analyzed. Patients were categorized based on their self-reported immigrant status as being Canadian or foreign born and based on their visual minority status (as European or a visual minority). We used logistic regression to examine associations between these patient characteristics of interest and patient adherence to statin medication 1 year after myocardial infarction (MI) and completion of cardiac rehabilitation, adjusting for age, sex, and comorbidities.

RESULTS

The dataset included outcome data on 1049 (64%) Canadian-born patients and 593 (36%) immigrants. There were 347 (21%) who identified as a visual minority. We report a nonsignificant trend in statin adherence 1 year after MI favouring foreign-born participants compared with Canadian-born participants (odds ratio [OR], 1.26; 95% confidence interval [CI], 0.91-1.68). Visual minorities were found to have no significant difference in statin adherence 1 year after MI compared with participants of European ethnicity (OR, 1.04; 95% CI, 0.72-1.51). Neither immigration status (OR, 0.91; 95% CI, 0.72-1.15) nor visual minority status (OR, 0.97; 95% CI, 0.73-1.28) were associated with cardiac rehabilitation completion.

CONCLUSIONS

Our findings offer limited support that immigrants with > 10 years of Canadian residency exposure experience greater adherence to statins 1 year after MI. Further research is required to better inform our understanding of secondary prevention strategy among immigrant populations.

摘要

背景

本研究的目的是按移民身份和种族评估对指南推荐的心脏二级预防治疗的依从性。

方法

我们对支持长期依从性和降低心血管事件(ISLAND)随机对照试验进行了一项回顾性子研究。分析了一组1642名参与者。患者根据自我报告的移民身份分为加拿大出生或外国出生,并根据其少数族裔身份(欧洲裔或少数族裔)进行分类。我们使用逻辑回归来检验这些感兴趣的患者特征与心肌梗死(MI)后1年及心脏康复完成后患者对他汀类药物治疗的依从性之间的关联,并对年龄、性别和合并症进行了调整。

结果

数据集包括1049名(64%)加拿大出生患者和593名(36%)移民的结局数据。有347名(21%)被认定为少数族裔。我们报告,与加拿大出生的参与者相比,MI后1年外国出生的参与者在他汀类药物依从性方面有不显著的趋势(优势比[OR],1.26;95%置信区间[CI],0.91 - 1.68)。与欧洲种族的参与者相比,少数族裔在MI后1年的他汀类药物依从性方面没有显著差异(OR,1.04;95%CI,0.72 - 1.51)。移民身份(OR,0.91;95%CI,0.72 - 1.15)和少数族裔身份(OR,0.97;95%CI,0.73 - 1.28)均与心脏康复完成情况无关。

结论

我们的研究结果提供了有限的支持,即有超过10年加拿大居住经历的移民在MI后1年对他汀类药物的依从性更高。需要进一步研究以更好地了解移民人群中的二级预防策略。

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