Department of Neurosurgery, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia; Department of Neurosurgery, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
Department of Diagnostic Radiology, Prince Mohammed Bin Abdulaziz Hospital, Riyadh, Saudi Arabia.
World Neurosurg. 2021 Nov;155:e177-e187. doi: 10.1016/j.wneu.2021.08.035. Epub 2021 Aug 14.
To determine whether vertical laminar fracture (VLF) can distinguish between AO type A3 and A4 fractures.
In a retrospective review of 111 consecutive acute thoracolumbar burst fractures, 5 reviewers independently analyzed computed tomography scans to classify fractures into A3 or A4 and to identify VLF. The following computed tomography parameters were measured: spinal canal stenosis >50%, anterior vertebral height ratio <50%, load sharing score >6, and local kyphosis >20°. We calculated the diagnostic performance of VLF in detecting A4 fracture. We compared the proportion of fractures with positive bony parameters, neurological deficit, dural tears, and surgical treatment between A3, A4 with VLF, and A4 without VLF.
VLF was present in 62/75 (83%) A4 fractures and 2/36 (5.5%) A3 fractures (P < 0.0001). VLF yielded a high specificity of 94% (95% confidence interval 81%-99%) and moderately high sensitivity of 83% (95% CI 72%-91%) in detecting A4 fractures. A significantly higher proportion of A4 fractures with VLF had neurological deficit (24% vs. 0, P = 0.05), spinal canal stenosis >50% (25% vs. 0, P = 0.04), and anterior vertebral height ratio <50% (24% vs. 0, P = 0.05) than A4 fractures with no VLF. Interrater and intrarater κ values for VLF and AO standard criterion were excellent (>0.85).
We found VLF to be highly specific, sensitive, and reliable in detecting A4 fractures. A higher proportion of A4 fractures with VLF had radiographic parameters and neurological deficit than A4 fractures with no VLF. VLF could be used as a severity modifier to further discriminate A3 and A4 fractures regarding severity and potentially guide treatment decision making.
确定垂直层状骨折(VLF)是否可以区分 AO 分型 A3 和 A4 骨折。
回顾性分析 111 例连续急性胸腰椎爆裂骨折患者,5 位评估者独立分析 CT 扫描,将骨折分为 A3 或 A4 型,并识别 VLF。测量以下 CT 参数:椎管狭窄>50%、前方椎体高度比<50%、负荷分担评分>6、局部后凸角>20°。我们计算了 VLF 检测 A4 骨折的诊断性能。我们比较了 A3、有 VLF 的 A4 和无 VLF 的 A4 骨折中阳性骨参数、神经功能缺损、硬脊膜撕裂和手术治疗的比例。
62/75(83%)例 A4 骨折和 2/36(5.5%)例 A3 骨折存在 VLF(P<0.0001)。VLF 检测 A4 骨折的特异性为 94%(95%置信区间 81%-99%),敏感性为 83%(95%CI 72%-91%),均较高。有 VLF 的 A4 骨折中神经功能缺损(24%比 0,P=0.05)、椎管狭窄>50%(25%比 0,P=0.04)和前方椎体高度比<50%(24%比 0,P=0.05)的比例明显高于无 VLF 的 A4 骨折。VLF 和 AO 标准准则的组内和组间 κ 值均为极好(>0.85)。
我们发现 VLF 对 A4 骨折的检测具有高度特异性、敏感性和可靠性。有 VLF 的 A4 骨折的比例高于无 VLF 的 A4 骨折,具有影像学参数和神经功能缺损。VLF 可作为严重程度的修饰因子,进一步区分 A3 和 A4 骨折的严重程度,并可能指导治疗决策。