Riethmuller D, Buisson A, Thong Vanh C, Istasse F, Valmary-Degano S, Michy T, Hoffmann P
Département de GO et médecine de la reproduction, CHU Grenoble Alpes, 38700 La Tronche, France.
Service d'anatomie et cytologie pathologique, département de gynécologie-obstétrique et médecine de la reproduction, CHU Grenoble Alpes, 38700 La Tronche, France.
Gynecol Obstet Fertil Senol. 2022 Feb;50(2):201-204. doi: 10.1016/j.gofs.2021.08.001. Epub 2021 Aug 14.
Buschke Lownestein's tumour is a giant acuminate condyloma characterised by its degenerative potential, its invasive nature and its recurrence after treatment. It is a rare condition, transmitted mainly by sexual transmission and induced by to the human papillomavirus (HPV). The discussion will be illustrated by a clinical case The treatment is still under discussion but surgery seems to be the best option. Management during pregnancy is more complex since it must take into account the mother and her fetus. The delivery route is still debated. The post-treatment evolution was satisfactory and without recurrence until the delivery which, due to the antecedent of 3 caesarean sections, was carried out by cesarean section. HPV vaccination, sex education and early treatment of condyloma lesions should prevent and in any case improve the prognosis of this disease.
Buschke-Lowenstein肿瘤是一种巨大尖锐湿疣，其特点是具有退变潜能、侵袭性以及治疗后易复发。它是一种罕见疾病，主要通过性传播，由人乳头瘤病毒（HPV）诱发。将通过一个临床病例来说明讨论情况。治疗方法仍在探讨中，但手术似乎是最佳选择。孕期管理更为复杂，因为必须兼顾母亲及其胎儿。分娩方式仍存在争议。治疗后的病情发展令人满意，直至分娩前均无复发，鉴于之前有3次剖宫产史，此次分娩通过剖宫产进行。HPV疫苗接种、性教育以及尖锐湿疣病变的早期治疗应能预防并在任何情况下改善该疾病的预后。
