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A new assay for glutathione S-transferase using [3H]-benzo(a)pyrene 4,5-oxide as substrate. Inducibility by various chemicals in different rat tissues compared to that of aryl hydrocarbon hydroxylase and epoxide hydratase.

作者信息

Van Cantfort J, Manil L, Gielen J E, Glatt H R, Oesch F

出版信息

Biochem Pharmacol. 1979;28(4):455-60. doi: 10.1016/0006-2952(79)90235-1.

DOI:10.1016/0006-2952(79)90235-1
PMID:34404
Abstract
摘要

相似文献

1
A new assay for glutathione S-transferase using [3H]-benzo(a)pyrene 4,5-oxide as substrate. Inducibility by various chemicals in different rat tissues compared to that of aryl hydrocarbon hydroxylase and epoxide hydratase.一种以[3H]-苯并(a)芘4,5-氧化物为底物的谷胱甘肽S-转移酶新检测方法。比较不同大鼠组织中各种化学物质对其的诱导性与芳烃羟化酶和环氧化物水化酶的诱导性。
Biochem Pharmacol. 1979;28(4):455-60. doi: 10.1016/0006-2952(79)90235-1.
2
Metabolism of benzo[a]pyrene in rat prostate glands following 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure.2,3,7,8-四氯二苯并对二恶英暴露后大鼠前列腺中苯并[a]芘的代谢
Carcinogenesis. 1981;2(9):823-31. doi: 10.1093/carcin/2.9.823.
3
The effects of gonadectomy on the hepatic activities of aryl hydrocarbon hydroxylase, epoxide hydratase, and glutathione S-transferase in Wistar rats pretreated with oral methadone . HCl.去势对口服美沙酮盐酸盐预处理的Wistar大鼠肝脏中芳烃羟化酶、环氧化物水合酶和谷胱甘肽S-转移酶活性的影响。
Can J Physiol Pharmacol. 1979 Mar;57(3):286-90. doi: 10.1139/y79-042.
4
The effects of cigarette smoke on the metabolism of [3H]benzo(a)pyrene by rat lung microsomes.香烟烟雾对大鼠肺微粒体中[3H]苯并(a)芘代谢的影响。
Cancer Res. 1977 Jul;37(7 Pt 1):2156-61.
5
the metabolism of drugs and carcinogens in isolated subcellular fractions of Drosophila melanogaster. II. Enzyme induction and metabolism of benzo[a]pyrene.黑腹果蝇离体亚细胞组分中药物和致癌物的代谢。II. 苯并[a]芘的酶诱导与代谢
Chem Biol Interact. 1981 Mar 1;34(2):145-59. doi: 10.1016/0009-2797(81)90127-7.
6
Metabolism of benzo(a)pyrene by the isolated perfused rat testis.苯并(a)芘在离体灌注大鼠睾丸中的代谢
Cancer Res. 1980 Sep;40(9):3297-303.
7
Effect of selected induction of microsomal and nuclear aryl hydrocarbon monooxygenase and epoxide hydrolase as well as cytoplasmic glutathione S-epoxide transferase on the covalent binding of the carcinogen benzo(a)pyrene to rat liver DNA in vivo.微粒体和细胞核芳烃单加氧酶、环氧化物水解酶以及细胞质谷胱甘肽S-环氧化物转移酶的特定诱导对致癌物苯并(a)芘在体内与大鼠肝脏DNA共价结合的影响。
J Cancer Res Clin Oncol. 1980;98(2):139-52. doi: 10.1007/BF00405958.
8
Effects of Panax ginseng extract on the benzo(a)pyrene metabolizing enzyme system.人参提取物对苯并(a)芘代谢酶系统的影响。
Drug Chem Toxicol. 1987;10(3-4):227-36. doi: 10.3109/01480548709042984.
9
Evaluation of the precision-cut liver and lung slice systems for the study of induction of CYP1, epoxide hydrolase and glutathione S-transferase activities.用于研究CYP1、环氧化物水解酶和谷胱甘肽S-转移酶活性诱导的精密肝切片和肺切片系统的评估。
Toxicology. 2007 Feb 28;231(1):68-80. doi: 10.1016/j.tox.2006.11.063. Epub 2006 Nov 26.
10
Drug metabolism in skin. Comparative activity of the mixed-function oxidases, epoxide hydratase, and glutathione S-transferase in liver and skin of the neonatal rat.皮肤中的药物代谢。新生大鼠肝脏和皮肤中混合功能氧化酶、环氧化物水解酶和谷胱甘肽S-转移酶的活性比较
Drug Metab Dispos. 1981 Jul-Aug;9(4):311-4.

引用本文的文献

1
Significant variation in mouse-skin aryl hydrocarbon hydroxylase inducibility as a function of the hair growth cycle.小鼠皮肤芳烃羟化酶诱导性随毛发生长周期的显著变化。
Br J Cancer. 1981 Feb;43(2):210-21. doi: 10.1038/bjc.1981.30.
2
Purification and characterization of a new cytosolic glutathione S-transferase (glutathione S-transferase X) from rat liver.从大鼠肝脏中纯化和鉴定一种新的胞质谷胱甘肽S-转移酶（谷胱甘肽S-转移酶X）。
Biochem J. 1983 Dec 1;215(3):617-25. doi: 10.1042/bj2150617.
3
Ontogenetic variation in rat liver, lung and kidney monooxygenase induction by low doses of benzo(A)pyrene and cigarette-smoke condensate.
低剂量苯并（A）芘和香烟烟雾冷凝物对大鼠肝脏、肺和肾脏单加氧酶诱导作用的个体发育变化。
Br J Cancer. 1981 Dec;44(6):902-10. doi: 10.1038/bjc.1981.290.
4
Comparison of benzo(a)pyrene metabolism in isolated perfused rat lung and liver.离体灌注大鼠肺和肝脏中苯并(a)芘代谢的比较。
Arch Toxicol. 1987 Jun;60(4):270-7. doi: 10.1007/BF01234665.