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[腹腔镜下对侵犯泌尿生殖器官的局部晚期直肠癌进行全盆腔脏器清除术]

[Laparoscopic Total Pelvic Exenteration of Locally Advanced Rectal Cancer Invading Urogenital Organs].

作者信息

Matsui Yuki, Tokuhara Katsuji, Ueyama Yosuke, Yoshioka Kazuhiko, Sekimoto Mitsugu

机构信息

Dept. of Gastroenterological Surgery, Kansai Medical University Medical Center.

出版信息

Gan To Kagaku Ryoho. 2021 Aug;48(8):1073-1076.

Abstract

Application of laparoscopic surgery(Lap)for colorectal cancer has expanded, and laparoscopic total pelvic exenteration (TPE)of locally advanced rectal cancer(LARC)invading the urogenital organs has been introduced in some institutions. In our institute, we have performed Lap TPE and posterior-TPE(PPE)in a total of 6 LARC patients so far. Here, we report the surgical technique of Lap TPE, and the associated surgical and short-term outcomes. We performed Lap TPE and Lap PPE in 3 patients each. Operation time was approximately 562 min, and the blood loss was 310 mL on an average. No patient developed postoperative complications above Clavien-Dindo Grade Ⅲ. One patient exhibited recurrence in the liver and another in peritoneum in the Lap PPE group. No recurrence was observed in the Lap TPE group(median follow-up period: 24.5 months). Although Lap TPE and PPE are difficult to perform and time consuming, it is suggested that these procedures may help reduce the intraoperative bleeding volume and shorten the length of postoperative hospital stay compared to open TPE and PPE.

摘要

腹腔镜手术在结直肠癌治疗中的应用不断拓展,一些机构已开展针对侵犯泌尿生殖器官的局部晚期直肠癌(LARC)的腹腔镜全盆腔脏器切除术(TPE)。在我院,截至目前我们共对6例LARC患者实施了腹腔镜TPE和后路TPE(PPE)。在此,我们报告腹腔镜TPE的手术技术以及相关的手术和短期结果。我们分别对3例患者实施了腹腔镜TPE和腹腔镜PPE。手术时间约为562分钟,平均失血量为310毫升。无患者出现Clavien-DindoⅢ级以上的术后并发症。在腹腔镜PPE组中,1例患者出现肝转移,另1例出现腹膜转移。腹腔镜TPE组未观察到复发(中位随访期:24.5个月)。尽管腹腔镜TPE和PPE操作困难且耗时,但与开放TPE和PPE相比,这些手术可能有助于减少术中出血量并缩短术后住院时间。

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