Department of Epilepsy, National Hospital for Neurology and Neurosurgery, London, UK
Department of Clinical and Experimental Epilepsy, Institute of Neurology, London, UK.
Pract Neurol. 2021 Dec;21(6):481-491. doi: 10.1136/practneurol-2019-002341. Epub 2021 Aug 17.
The semiology of epileptic seizures reflects activation, or dysfunction, of areas of brain (often termed the symptomatogenic zone) as a seizure begins and evolves. Specific semiologies in focal epilepsies provide an insight into the location of the seizure onset zone, which is particularly important for presurgical epilepsy assessment. The correct diagnosis of paroxysmal events also depends on the clinician being familiar with the spectrum of semiologies. Here, we summarise the current literature on localisation in focal epilepsies using illustrative cases and discussing possible pitfalls in localisation.
癫痫发作的症状学反映了癫痫发作开始和演变时大脑区域的激活或功能障碍（通常称为症状发生区）。局灶性癫痫的特定症状学提供了对发作起始区位置的深入了解，这对于术前癫痫评估尤为重要。阵发性事件的正确诊断还取决于临床医生对症状学谱的熟悉程度。在这里，我们使用说明性病例总结了局灶性癫痫中定位的当前文献，并讨论了定位中的可能陷阱。
