Department of Medicine, Universidade de Taubaté, Taubaté, Brazil.
Neurosurgery Service, Hospital Regional do Vale do Paraíba, Taubaté, Brazil.
Br J Neurosurg. 2024 Jun;38(3):756-760. doi: 10.1080/02688697.2021.1967290. Epub 2021 Aug 18.
Papillary glioneuronal tumour is an entity described as grade I neuronal-glial tumour by the World Health Organization. Headaches, seizures, vomiting, language or visual disturbances, and hemiparesis are the most common clinical findings. This tumour typically presents as cystic with enhancing mural nodule in the cerebral hemisphere. In this paper, we reported a case of a papillary glioneuronal tumour in a young adult whose magnetic resonance imaging revealed a solid tumour in the cerebral aqueduct. The tumour was totally resected surgically 13 years ago. The histological and immunohistochemical examination determined the diagnosis. No further therapy was necessary. Currently, the patient presents no neurologic signs or symptoms and there is no radiologic evidence of tumour relapse. The case of papillary glioneuronal tumour reported here displayed unusual location and radiologic features. The long duration of follow-up of this case with no tumour relapse enhances that the preferred management for this type of tumour is its total surgical resection.
乳头状胶质神经元肿瘤是一种被世界卫生组织(WHO)定义为 1 级神经元-神经胶质肿瘤的实体瘤。头痛、癫痫、呕吐、语言或视觉障碍以及偏瘫是最常见的临床发现。这种肿瘤通常表现为脑半球囊性伴增强壁结节。本文报道了一例青年成人的乳头状胶质神经元肿瘤,其磁共振成像显示脑导水管内实性肿瘤。该肿瘤 13 年前曾行手术完全切除。组织学和免疫组化检查确定了诊断。无需进一步治疗。目前,患者无神经体征或症状,且无肿瘤复发的影像学证据。本例乳头状胶质神经元肿瘤表现出不同寻常的位置和影像学特征。该病例长期随访无肿瘤复发,表明此类肿瘤的首选治疗方法是完全手术切除。