肥胖品系（OS）鸡各器官中产生甲状腺球蛋白自身抗体细胞的免疫荧光定位
Immunofluorescence localization of thyroglobulin autoantibody producing cells in various organs of obese strain (OS) chickens.
作者信息
Kofler R, Wick G
出版信息
Folia Biol (Praha). 1977;23(6):428-9.
PMID:344076
Abstract
All major lymphoid organs from animals of the Obese strain (OS) of chickens which develop a spontaneous autoimmune thyroiditis with circulating thyroglobulin autoantibodies (Tg-AAb) were investigated for Tg-AAb producing cells using the immunofluorescence method (IF). No Tg-binding cells could be detected in spleen, bursa. Harderian glands, thymus, coecal tonsils or bone marrow. The infiltrated thyroid gland was shown to be the only site of Tg-AAb production detectable by IF.
摘要
对患自发性自身免疫性甲状腺炎且伴有循环甲状腺球蛋白自身抗体（Tg-AAb）的肥胖品系（OS）鸡的所有主要淋巴器官，采用免疫荧光法（IF）研究产生Tg-AAb的细胞。在脾脏、法氏囊、哈德氏腺、胸腺、盲肠扁桃体或骨髓中未检测到结合Tg的细胞。经IF检测，浸润的甲状腺是唯一可检测到Tg-AAb产生的部位。
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