Wade W G, Addy M
Department of Periodontology, Dental School, University of Wales College of Medicine, Heath Park, Cardiff, UK.
J Appl Bacteriol. 1987 Nov;63(5):455-7. doi: 10.1111/j.1365-2672.1987.tb04868.x.
Niridazole, metronidazole and tetracycline were compared for their activity against subgingival bacteria from patients with chronic periodontitis. Niridazole was consistently more effective than the other drugs against obligate anaerobes and exhibited some activity against facultative organisms. It was concluded that niridazole has potential for topical use in chronic periodontitis.