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Comparison of in vitro activity of niridazole, metronidazole and tetracycline against subgingival bacteria in chronic periodontitis.

作者信息

Wade W G, Addy M

机构信息

Department of Periodontology, Dental School, University of Wales College of Medicine, Heath Park, Cardiff, UK.

出版信息

J Appl Bacteriol. 1987 Nov;63(5):455-7. doi: 10.1111/j.1365-2672.1987.tb04868.x.

Abstract

Niridazole, metronidazole and tetracycline were compared for their activity against subgingival bacteria from patients with chronic periodontitis. Niridazole was consistently more effective than the other drugs against obligate anaerobes and exhibited some activity against facultative organisms. It was concluded that niridazole has potential for topical use in chronic periodontitis.

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