• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

Increased α-Synuclein Level in CD45+ Blood Cells in Asymptomatic Carriers of GBA Mutations.

作者信息

Emelyanov Anton, Usenko Tatiana, Nikolaev Mikhail, Senkevich Konstantin, Kulabukhova Darya, Lavrinova Anna, Andoskin Pavel, Miliukhina Irina, Pchelina Sofya

机构信息

Petersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Centre "Kurchatov Institute,", St. Petersburg, Russian Federation.

First Pavlov State Medical University of St. Petersburg, St. Petersburg, Russian Federation.

出版信息

Mov Disord. 2021 Aug;36(8):1997-1998. doi: 10.1002/mds.28688.

DOI:10.1002/mds.28688
PMID:34409693
Abstract
摘要

相似文献

1
Increased α-Synuclein Level in CD45+ Blood Cells in Asymptomatic Carriers of GBA Mutations.GBA突变无症状携带者CD45 +血细胞中α-突触核蛋白水平升高。
Mov Disord. 2021 Aug;36(8):1997-1998. doi: 10.1002/mds.28688.
2
Reply to: "Increased alpha-Synuclein Level in CD45 Blood Cells in Asymptomatic Carriers of GBA Mutations".回复:“GBA突变无症状携带者CD45血细胞中α-突触核蛋白水平升高”
Mov Disord. 2021 Aug;36(8):1998-1999. doi: 10.1002/mds.28678.
3
Involvement of Gaucher Disease Mutations in Parkinson Disease.戈谢病突变与帕金森病的关联。
Curr Protein Pept Sci. 2017;18(7):758-764. doi: 10.2174/1389203717666160311115956.
4
Glucosylsphingosine Promotes α-Synuclein Pathology in Mutant GBA-Associated Parkinson's Disease.葡糖神经鞘氨醇在突变型GBA相关帕金森病中促进α-突触核蛋白病变。
J Neurosci. 2017 Oct 4;37(40):9617-9631. doi: 10.1523/JNEUROSCI.1525-17.2017. Epub 2017 Aug 28.
5
Augmentation of phenotype in a transgenic Parkinson mouse heterozygous for a Gaucher mutation.转 Gaucher 突变杂合子帕金森病小鼠表型增强。
Brain. 2014 Dec;137(Pt 12):3235-47. doi: 10.1093/brain/awu291. Epub 2014 Oct 27.
6
Oligomeric α-synuclein and glucocerebrosidase activity levels in GBA-associated Parkinson's disease.GBA相关帕金森病中寡聚α-突触核蛋白和葡萄糖脑苷脂酶活性水平
Neurosci Lett. 2017 Jan 1;636:70-76. doi: 10.1016/j.neulet.2016.10.039. Epub 2016 Oct 22.
7
[Plasma Exosomes in Inherited Forms of Parkinson's Disease].[帕金森病遗传形式中的血浆外泌体]
Mol Biol (Mosk). 2021 Mar-Apr;55(2):338-345. doi: 10.31857/S0026898421010092.
8
Glucocerebrosidase haploinsufficiency in A53T α-synuclein mice impacts disease onset and course.A53Tα-突触核蛋白小鼠糖脑苷脂酶单倍体不足影响疾病的发病和进程。
Mol Genet Metab. 2017 Dec;122(4):198-208. doi: 10.1016/j.ymgme.2017.11.001. Epub 2017 Nov 21.
9
Profiling the Biochemical Signature of GBA-Related Parkinson's Disease in Peripheral Blood Mononuclear Cells.分析外周血单个核细胞中 GBA 相关帕金森病的生化特征。
Mov Disord. 2021 May;36(5):1267-1272. doi: 10.1002/mds.28496. Epub 2021 Feb 22.
10
Alpha-synuclein dimerization in erythrocytes of patients with genetic and non-genetic forms of Parkinson's Disease.帕金森病遗传型和非遗传型患者红细胞中的α-突触核蛋白二聚化
Neurosci Lett. 2018 Apr 13;672:145-149. doi: 10.1016/j.neulet.2017.11.012. Epub 2017 Nov 10.

引用本文的文献

1
A novel allosteric GCase modulator prevents Tau accumulation in GBA1 and GBA1 cellular models.一种新型变构葡糖脑苷脂酶调节剂可防止GBA1及GBA1细胞模型中tau蛋白积聚。
Sci Rep. 2025 May 21;15(1):17646. doi: 10.1038/s41598-025-02346-8.
2
Tau accumulation in degradative organelles is associated to lysosomal stress.tau 蛋白在降解性细胞器中的积累与溶酶体应激有关。
Sci Rep. 2023 Oct 21;13(1):18024. doi: 10.1038/s41598-023-44979-7.
3
Who is at Risk of Parkinson Disease? Refining the Preclinical Phase of GBA1 and LRRK2 Variant Carriers: a Clinical, Biochemical, and Imaging Approach.
谁有患帕金森病的风险?GBAl 和 LRRK2 变异携带者临床前阶段的精细化:临床、生化和影像学方法。
Curr Neurol Neurosci Rep. 2023 Apr;23(4):121-130. doi: 10.1007/s11910-023-01259-1. Epub 2023 Mar 7.
4
a-Synuclein and lipids in erythrocytes of Gaucher disease carriers and patients before and after enzyme replacement therapy.戈谢病患者和携带者红细胞中的α-突触核蛋白和脂质在酶替代治疗前后的变化。
PLoS One. 2023 Feb 3;18(2):e0277602. doi: 10.1371/journal.pone.0277602. eCollection 2023.
5
Neuroinflammation and Immune Changes in Prodromal Parkinson's Disease and Other Synucleinopathies.神经炎症与前驱帕金森病及其他突触核蛋白病中的免疫改变。
J Parkinsons Dis. 2022;12(s1):S149-S163. doi: 10.3233/JPD-223245.